Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2820940..2821574 Replicon chromosome
Accession NZ_CP040872
Organism Agromyces laixinhei strain HY052

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FHG54_RS13335 Protein ID WP_139417703.1
Coordinates 2820940..2821359 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FHG54_RS13340 Protein ID WP_139417704.1
Coordinates 2821350..2821574 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHG54_RS13310 2816360..2817232 - 873 WP_139417699.1 Fpg/Nei family DNA glycosylase -
FHG54_RS13315 2817364..2817546 - 183 WP_139417700.1 CsbD family protein -
FHG54_RS13320 2817884..2819155 + 1272 WP_139417701.1 glutaminase -
FHG54_RS13325 2819174..2819761 + 588 WP_139417702.1 hypothetical protein -
FHG54_RS13330 2819928..2820399 + 472 Protein_2621 class I SAM-dependent methyltransferase -
FHG54_RS13335 2820940..2821359 - 420 WP_139417703.1 PIN domain nuclease Toxin
FHG54_RS13340 2821350..2821574 - 225 WP_139417704.1 hypothetical protein Antitoxin
FHG54_RS13345 2821762..2822555 - 794 Protein_2624 alpha/beta hydrolase -
FHG54_RS13350 2822801..2823058 - 258 WP_139417705.1 type II toxin-antitoxin system RelE/ParE family toxin -
FHG54_RS13355 2823071..2823313 - 243 WP_139417706.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
FHG54_RS13360 2823451..2824209 - 759 WP_139417707.1 MerR family transcriptional regulator -
FHG54_RS13365 2824258..2824740 + 483 WP_210415509.1 hypothetical protein -
FHG54_RS13370 2824817..2825890 - 1074 WP_139417709.1 redox-regulated ATPase YchF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15048.33 Da        Isoelectric Point: 4.7443

>T127142 WP_139417703.1 NZ_CP040872:c2821359-2820940 [Agromyces laixinhei]
VAVTSWLVDKSAYVRMQGGQAESLAEWNSRIERGLLRLSPVTRLELGFSARSGQAGREAFGLPPLSLMPIEHLTPAMEDR
AFEVQMLLADRGQHRAPSIPDLLIAATAEKAGLTVLAVDKDFELIAEVTGQPVETLALV

Download         Length: 420 bp

>T127142 NZ_CP040872:c2821359-2820940 [Agromyces laixinhei]
GTGGCGGTGACGAGCTGGCTGGTCGACAAGTCGGCATACGTGCGCATGCAGGGAGGTCAAGCGGAGAGCTTGGCTGAGTG
GAACTCGCGCATCGAGCGTGGGCTGCTGCGTCTTTCGCCGGTGACGCGGCTCGAACTTGGCTTCTCTGCCCGTTCAGGTC
AAGCAGGTCGCGAGGCTTTCGGGCTGCCCCCGCTGTCGCTCATGCCGATCGAGCACCTCACACCCGCGATGGAGGACCGC
GCCTTCGAGGTGCAGATGCTCCTTGCCGACCGTGGCCAGCATCGCGCCCCGTCCATCCCGGATCTGCTCATCGCAGCGAC
CGCGGAGAAGGCTGGGCTGACGGTCTTGGCCGTTGACAAGGACTTCGAGCTCATTGCTGAGGTCACCGGGCAGCCCGTGG
AGACGCTCGCACTGGTCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8014.85 Da        Isoelectric Point: 4.1403

>AT127142 WP_139417704.1 NZ_CP040872:c2821574-2821350 [Agromyces laixinhei]
MSNVLIRGLSEAAVEHIDAEAAALGLSRNEFLRRRLEQDASTPVAATVTADDWSRSAAAFEDLADPDVMDAAWR

Download         Length: 225 bp

>AT127142 NZ_CP040872:c2821574-2821350 [Agromyces laixinhei]
ATGTCGAACGTGCTGATCCGTGGACTGAGTGAGGCTGCCGTCGAGCACATCGATGCTGAGGCGGCGGCCCTCGGACTATC
GCGCAACGAGTTCCTTCGTCGGCGACTCGAGCAGGACGCCTCGACTCCGGTCGCCGCGACGGTCACTGCCGATGACTGGA
GTCGCTCGGCGGCGGCGTTCGAGGACCTTGCCGATCCTGACGTGATGGATGCGGCGTGGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References