Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 878365..879085 Replicon chromosome
Accession NZ_CP040872
Organism Agromyces laixinhei strain HY052

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FHG54_RS04205 Protein ID WP_139416159.1
Coordinates 878657..879085 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FHG54_RS04200 Protein ID WP_139416158.1
Coordinates 878365..878619 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHG54_RS04180 873964..874371 + 408 WP_139418296.1 HD domain-containing protein -
FHG54_RS04185 874395..875021 - 627 WP_198169783.1 flavin reductase family protein -
FHG54_RS04190 875522..876886 + 1365 WP_139416156.1 hypothetical protein -
FHG54_RS04195 876928..878181 - 1254 WP_139416157.1 plasmid pRiA4b ORF-3 family protein -
FHG54_RS04200 878365..878619 + 255 WP_139416158.1 antitoxin Antitoxin
FHG54_RS04205 878657..879085 + 429 WP_139416159.1 PIN domain-containing protein Toxin
FHG54_RS04210 879327..879770 + 444 WP_139416160.1 VOC family protein -
FHG54_RS04215 879881..881398 - 1518 WP_168197096.1 plasmid pRiA4b ORF-3 family protein -
FHG54_RS04225 881912..883363 + 1452 WP_139416163.1 ADP-ribosylglycohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15592.83 Da        Isoelectric Point: 6.6055

>T127141 WP_139416159.1 NZ_CP040872:878657-879085 [Agromyces laixinhei]
MRLVDANVLLYAVDRGADHHRAAKTWLDAALRGPQTVLLPWVSVLAFVRLVSHPSVYEHPLPVSDALDVVDTWLAAPSVV
TPEPDARHLARIRELLGATGRGGNLVNDAHLAALALQHRATVITFDNDFGRFPDVLWERPTA

Download         Length: 429 bp

>T127141 NZ_CP040872:878657-879085 [Agromyces laixinhei]
ATGAGACTCGTCGATGCGAACGTCCTGCTCTACGCGGTCGATCGCGGGGCCGACCATCACCGCGCGGCCAAGACCTGGCT
CGACGCGGCGCTCCGCGGGCCTCAGACCGTGCTGTTGCCCTGGGTCAGCGTGCTCGCGTTCGTGCGCCTGGTGAGTCATC
CGTCGGTGTACGAGCATCCGCTGCCGGTGTCCGACGCGCTCGACGTGGTCGACACGTGGCTCGCTGCCCCCTCGGTCGTC
ACACCCGAGCCTGATGCACGCCACCTGGCGCGCATCCGCGAACTGCTGGGTGCTACCGGTCGCGGTGGCAACCTCGTGAA
CGACGCCCACCTCGCGGCGCTTGCGCTGCAGCACCGAGCGACCGTGATCACGTTCGACAACGACTTCGGCCGTTTTCCCG
ATGTTCTGTGGGAGCGACCGACCGCGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9259.65 Da        Isoelectric Point: 8.9715

>AT127141 WP_139416158.1 NZ_CP040872:878365-878619 [Agromyces laixinhei]
VRTTITLTADADALVRRVMRERGLSFRDAVNFAIIAGLAPVDRSAAVETPTFDLGRARLPLDRAIALAAELEDEQLLRKR
EQGK

Download         Length: 255 bp

>AT127141 NZ_CP040872:878365-878619 [Agromyces laixinhei]
GTGCGCACCACCATCACGTTGACCGCCGACGCCGACGCACTCGTGCGCCGGGTCATGCGTGAACGCGGGCTCTCGTTCAG
AGACGCGGTGAATTTCGCGATCATCGCGGGGCTCGCCCCTGTCGACCGATCAGCGGCCGTCGAGACCCCGACGTTCGACC
TCGGCCGGGCACGGCTGCCGCTCGACCGCGCGATCGCCCTCGCCGCCGAGCTCGAAGACGAGCAGCTGCTGCGCAAGCGG
GAGCAGGGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References