Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045992..2046137 Replicon chromosome
Accession NZ_CP040833
Organism Klebsiella pneumoniae strain SH12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2046028..2046130 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045992..2046137 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHY43_RS10070 (FHY43_10220) 2041122..2043182 + 2061 WP_004151449.1 oligopeptidase B -
FHY43_RS10075 (FHY43_10225) 2043186..2043845 - 660 WP_002911407.1 exodeoxyribonuclease X -
FHY43_RS10080 (FHY43_10230) 2043924..2044154 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FHY43_RS10085 (FHY43_10235) 2044267..2044641 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FHY43_RS10090 (FHY43_10240) 2044645..2045514 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FHY43_RS10095 (FHY43_10245) 2045531..2045869 + 339 WP_002911404.1 YebY family protein -
- 2045992..2046137 - 146 - - Antitoxin
- 2046028..2046130 + 103 - - Toxin
FHY43_RS10100 2046505..2046648 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FHY43_RS10105 (FHY43_10255) 2046753..2047721 - 969 WP_004151446.1 VirK/YbjX family protein -
FHY43_RS10110 (FHY43_10260) 2047878..2048531 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
FHY43_RS10115 (FHY43_10265) 2048528..2048719 - 192 WP_002911395.1 YebW family protein -
FHY43_RS10120 (FHY43_10270) 2048817..2049056 - 240 WP_002911393.1 YebV family protein -
FHY43_RS10125 (FHY43_10275) 2049172..2050605 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T127068 NZ_CP040833:2046028-2046130 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT127068 NZ_CP040833:c2046137-2045992 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References