Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 555008..555516 Replicon chromosome
Accession NZ_CP040792
Organism Clavibacter californiensis strain CFBP 8216

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FGD68_RS02930 Protein ID WP_119372886.1
Coordinates 555008..555268 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FGD68_RS02935 Protein ID WP_086527408.1
Coordinates 555265..555516 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGD68_RS02895 (FGD68_02895) 550219..550803 + 585 WP_237609750.1 TetR/AcrR family transcriptional regulator -
FGD68_RS02900 (FGD68_02900) 550816..551673 - 858 WP_119372892.1 3-hydroxyacyl-CoA dehydrogenase -
FGD68_RS02905 (FGD68_02905) 551864..552721 + 858 WP_119372891.1 phosphatase PAP2 family protein -
FGD68_RS02910 (FGD68_02910) 552750..552989 + 240 WP_119372890.1 hypothetical protein -
FGD68_RS02915 (FGD68_02915) 553027..553449 + 423 WP_119372889.1 alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB -
FGD68_RS02920 (FGD68_02920) 553477..554526 - 1050 WP_119372888.1 LLM class flavin-dependent oxidoreductase -
FGD68_RS02925 (FGD68_02925) 554653..554994 + 342 WP_119372887.1 DUF2200 domain-containing protein -
FGD68_RS02930 (FGD68_02930) 555008..555268 - 261 WP_119372886.1 Txe/YoeB family addiction module toxin Toxin
FGD68_RS02935 (FGD68_02935) 555265..555516 - 252 WP_086527408.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FGD68_RS02940 (FGD68_02940) 555566..555817 - 252 WP_119372894.1 DUF2283 domain-containing protein -
FGD68_RS02945 (FGD68_02945) 555817..556392 - 576 WP_119372885.1 TetR/AcrR family transcriptional regulator -
FGD68_RS02950 (FGD68_02950) 556490..557629 + 1140 WP_119372884.1 zinc-binding alcohol dehydrogenase family protein -
FGD68_RS02955 (FGD68_02955) 557663..557962 + 300 WP_119372883.1 rhodanese-like domain-containing protein -
FGD68_RS02960 (FGD68_02960) 558002..558586 + 585 WP_119372882.1 YdeI/OmpD-associated family protein -
FGD68_RS02965 (FGD68_02965) 558599..559183 - 585 WP_119372881.1 GNAT family protein -
FGD68_RS02970 (FGD68_02970) 559379..560098 - 720 WP_119373904.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10062.47 Da        Isoelectric Point: 8.9817

>T126963 WP_119372886.1 NZ_CP040792:c555268-555008 [Clavibacter californiensis]
VSRQLAFDADGWKDCTYWQSQDRKTLKRINALIRDVMRDPFAGPGKPEPLKHILSGAWSRRIDEANRLVYLVTDEHIVIL
QARDHY

Download         Length: 261 bp

>T126963 NZ_CP040792:c555268-555008 [Clavibacter californiensis]
GTGAGCCGACAGCTCGCCTTCGACGCCGACGGCTGGAAGGACTGCACCTACTGGCAGAGCCAGGATCGCAAGACGCTCAA
GCGGATCAACGCGCTGATCCGGGACGTGATGCGCGACCCGTTCGCGGGACCGGGCAAGCCCGAGCCCCTCAAGCACATCC
TCTCGGGCGCGTGGTCACGGCGCATCGACGAGGCGAATCGCCTGGTCTATCTGGTCACCGACGAGCACATCGTGATCCTG
CAAGCGCGCGACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9220.30 Da        Isoelectric Point: 5.0981

>AT126963 WP_086527408.1 NZ_CP040792:c555516-555265 [Clavibacter californiensis]
MSAITASDARRNLFGLIQQVNDDHSPVEVVSKHGNAVLISKDDFDAITETAYLLRNAKGAQRLLGALERARRGEFETHEL
IEE

Download         Length: 252 bp

>AT126963 NZ_CP040792:c555516-555265 [Clavibacter californiensis]
ATGTCCGCCATCACCGCATCCGACGCTCGTCGGAACCTGTTCGGACTCATCCAGCAGGTCAACGACGACCACTCTCCCGT
GGAGGTCGTCTCGAAGCACGGCAACGCCGTCTTGATCTCGAAGGACGACTTCGACGCGATCACGGAGACGGCCTACCTGC
TCCGGAACGCCAAGGGTGCGCAGCGGCTGCTGGGCGCGCTCGAGCGGGCACGCCGAGGCGAGTTCGAGACGCACGAGCTG
ATCGAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References