Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 940264..941164 | Replicon | chromosome |
| Accession | NZ_CP040774 | ||
| Organism | Mycoplasmopsis bovis strain KRB1 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | - |
| Locus tag | COR49_RS04130 | Protein ID | WP_235129226.1 |
| Coordinates | 940264..940557 (-) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | COR49_RS04135 | Protein ID | WP_013456322.1 |
| Coordinates | 940550..941164 (-) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| COR49_RS04425 (COR49_04070) | 936411..937091 | + | 681 | WP_276513387.1 | variable surface lipoprotein | - |
| COR49_RS04430 (COR49_04075) | 937350..937922 | - | 573 | WP_157823757.1 | variable surface lipoprotein | - |
| COR49_RS04115 (COR49_04080) | 938042..938578 | - | 537 | WP_276513392.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| COR49_RS04120 (COR49_04085) | 938830..939804 | + | 975 | WP_235129224.1 | transposase | - |
| COR49_RS04125 | 939983..940261 | + | 279 | WP_232952569.1 | hypothetical protein | - |
| COR49_RS04130 (COR49_04090) | 940264..940557 | - | 294 | WP_235129226.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| COR49_RS04135 (COR49_04095) | 940550..941164 | - | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| COR49_RS04140 (COR49_04100) | 941347..941922 | + | 576 | WP_214469309.1 | variable surface lipoprotein | - |
| COR49_RS04145 (COR49_04105) | 941965..942729 | - | 765 | WP_115287438.1 | variable surface lipoprotein | - |
| COR49_RS04150 (COR49_04110) | 943015..943764 | + | 750 | WP_013456123.1 | tyrosine-type recombinase/integrase | - |
| COR49_RS04160 (COR49_04120) | 944163..946007 | + | 1845 | WP_013456272.1 | ribonuclease J | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11179.22 Da Isoelectric Point: 10.4883
>T126951 WP_235129226.1 NZ_CP040774:c940557-940264 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNKKVLV
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNKKVLV
Download Length: 294 bp
>T126951 NZ_CP040774:c940557-940264 [Mycoplasmopsis bovis]
ATGAATAAAAATAAATTAATAAGTTTGTGTCATAAAACTGCTGATGAAAATAACGCAAATTTCAATGTTGTTTTAATTCA
ATATTTTATGGAAAGCATTCTACGAAGAATATCTAAAAGTAATGAGAGAGACAATTTTGTGTTCAAGGGCGGTTTTCTTT
TATCTAACATTATGGGGTTAGATAAAAGAGCTACAATGGATATTGATTTGGAGCTAATAAAAACTCAAAAGATAAGTGCT
TCTAAAATATTAGAAAAATTTAAAAGTATATTAAATAAAAAAGTTTTAGTGTAA
ATGAATAAAAATAAATTAATAAGTTTGTGTCATAAAACTGCTGATGAAAATAACGCAAATTTCAATGTTGTTTTAATTCA
ATATTTTATGGAAAGCATTCTACGAAGAATATCTAAAAGTAATGAGAGAGACAATTTTGTGTTCAAGGGCGGTTTTCTTT
TATCTAACATTATGGGGTTAGATAAAAGAGCTACAATGGATATTGATTTGGAGCTAATAAAAACTCAAAAGATAAGTGCT
TCTAAAATATTAGAAAAATTTAAAAGTATATTAAATAAAAAAGTTTTAGTGTAA
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT126951 WP_013456322.1 NZ_CP040774:c941164-940550 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
>AT126951 NZ_CP040774:c941164-940550 [Mycoplasmopsis bovis]
ATGGAACAAAAAAACTTAAATTCGAAATATTACAATGCAATTTTTAAACTGTTACATAAAAATAACGGTGTTATCACATA
TAAGCAACTAAAAGAAAACAATATATCTTCTATATATTTAACAAGAATGATAACAAAAGGCGTTCTTATTAGAAGAGCTA
AAGGCATTTATATTCTTAGTGATGGACATTACGATGAATATTATTTCTTAAGCAAAAACTATAAATCGTTAATCTTTTCT
CATTATAGTGCACTATATTTAAATAATATTATTGACATTTTTCCGCATCAAATTGACGTTACAGTTTACAGTGGCTATAA
TGCAAAAGGCATTAAGAAGCATGCAAATGTTTACTACTGTGATAGGAATAAACATTCAATTGGACTATCTGAATCAAAAA
CATTATTTGGAAACAAAGTTAAGGTATATGACTTTGAGAGAACAATTTGTGATTTTGTAAAACTACGCAAGAAAACAGAT
AGCGAAATCTTTTCTAAGCTTATTAGTGCATATATTAAATATGAAAATAGAGATTGAAAAAAATTGTATGAATACGCCTA
TGAATTAGGCATACACAAAAAAATATCGGAGATATTTGAACTATTTTATGAATAA
ATGGAACAAAAAAACTTAAATTCGAAATATTACAATGCAATTTTTAAACTGTTACATAAAAATAACGGTGTTATCACATA
TAAGCAACTAAAAGAAAACAATATATCTTCTATATATTTAACAAGAATGATAACAAAAGGCGTTCTTATTAGAAGAGCTA
AAGGCATTTATATTCTTAGTGATGGACATTACGATGAATATTATTTCTTAAGCAAAAACTATAAATCGTTAATCTTTTCT
CATTATAGTGCACTATATTTAAATAATATTATTGACATTTTTCCGCATCAAATTGACGTTACAGTTTACAGTGGCTATAA
TGCAAAAGGCATTAAGAAGCATGCAAATGTTTACTACTGTGATAGGAATAAACATTCAATTGGACTATCTGAATCAAAAA
CATTATTTGGAAACAAAGTTAAGGTATATGACTTTGAGAGAACAATTTGTGATTTTGTAAAACTACGCAAGAAAACAGAT
AGCGAAATCTTTTCTAAGCTTATTAGTGCATATATTAAATATGAAAATAGAGATTGAAAAAAATTGTATGAATACGCCTA
TGAATTAGGCATACACAAAAAAATATCGGAGATATTTGAACTATTTTATGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|