Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079055..2079200 Replicon chromosome
Accession NZ_CP040033
Organism Klebsiella pneumoniae strain KPC160117

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079091..2079193 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079055..2079200 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FDK26_RS10390 2074185..2076245 + 2061 WP_004151449.1 oligopeptidase B -
FDK26_RS10395 2076249..2076908 - 660 WP_002911407.1 exodeoxyribonuclease X -
FDK26_RS10400 2076987..2077217 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FDK26_RS10405 2077330..2077704 + 375 WP_039819395.1 CopC domain-containing protein YobA -
FDK26_RS10410 2077708..2078577 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
FDK26_RS10415 2078594..2078932 + 339 WP_002911404.1 YebY family protein -
- 2079055..2079200 - 146 - - Antitoxin
- 2079091..2079193 + 103 - - Toxin
FDK26_RS10420 2079569..2079712 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
FDK26_RS10425 2079817..2080785 - 969 WP_014907334.1 VirK/YbjX family protein -
FDK26_RS10430 2080942..2081595 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
FDK26_RS10435 2081592..2081783 - 192 WP_002911395.1 YebW family protein -
FDK26_RS10440 2081881..2082120 - 240 WP_002911393.1 YebV family protein -
FDK26_RS10445 2082236..2083669 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124805 NZ_CP040033:2079091-2079193 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT124805 NZ_CP040033:c2079200-2079055 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References