Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 161187..162627 Replicon chromosome
Accession NZ_CP040021
Organism Salinivibrio kushneri strain AL184

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag FCN78_RS00765 Protein ID WP_077659133.1
Coordinates 161740..162627 (+) Length 296 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag FCN78_RS00760 Protein ID WP_077659132.1
Coordinates 161187..161711 (+) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCN78_RS00740 156284..157600 + 1317 WP_077578197.1 TRAP transporter large permease subunit -
FCN78_RS00745 157680..158180 + 501 WP_077659128.1 gluconokinase -
FCN78_RS00750 158177..159667 + 1491 WP_077659129.1 NADP-dependent phosphogluconate dehydrogenase -
FCN78_RS00755 159777..160778 + 1002 WP_077659130.1 gluconate operon transcriptional repressor GntR -
FCN78_RS00760 161187..161711 + 525 WP_077659132.1 hypothetical protein Antitoxin
FCN78_RS00765 161740..162627 + 888 WP_077659133.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FCN78_RS00770 162822..163028 + 207 WP_201258656.1 virulence RhuM family protein -
FCN78_RS00775 163516..165042 + 1527 WP_077659135.1 DNA (cytosine-5-)-methyltransferase -
FCN78_RS00780 165282..166766 + 1485 WP_077659137.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-258)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 296 a.a.        Molecular weight: 33967.82 Da        Isoelectric Point: 5.6781

>T124755 WP_077659133.1 NZ_CP040021:161740-162627 [Salinivibrio kushneri]
MLKQQIRQIVQSNPDYASVTPVIEKEILHHDIMDVLIKQGVLQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSEFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKVSIVKAPNRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDMVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKILVEKKLNARHKQTDDFRQALSAALTKLMSEEE
VHNDFNMEMSRFIPQKIKERTIDNSEYWAYVQGEVTAIASELLDDGTPKNPFDMG

Download         Length: 888 bp

>T124755 NZ_CP040021:161740-162627 [Salinivibrio kushneri]
ATGCTGAAGCAACAAATTCGCCAAATCGTACAGTCAAACCCTGACTATGCATCAGTCACGCCCGTGATCGAAAAAGAGAT
CTTGCATCATGACATTATGGATGTGCTGATCAAGCAAGGCGTTCTGCAGCGGTTAACCTTTATTGGCGGCACCTCACTAC
GCATGTGCTACAACAGCAGTCGATTGTCAGAAGATCTTGATTTCAACGGTGGCCATGACTTCAAACCGTCCGAGTTTGAG
GGGCTGGAGTCTGAGATACAGACTTATATCCAAAATAAGTATGAAACTGAAGTGTGGGTCAACAAGCCCTCTGGCGAGCA
GCAAGGGGATACCGTTTCGTGGAAGGTTAGTATCGTGAAAGCGCCTAATCGTCCTGATTTACCAAGACAAAAAATGCATA
TTGACGTCTGTGCCATACCTTCATTCGATATCGAAAAGCGTCCTTTAATCAATCATTACGATATGGTTGTACCGACAGAA
GGTATCTTAGTTCCTGTTCAATCACTACAAGAAACATTGGCCGATAAGCTTATTGCATTAGCGTATCGAGCAAGGCGTAT
CAAGCCTCGTGATATTTGGGATATTGTTTGGATTAAGCAGCGCGGGATTGATTTATCCAAGATATTGGTTGAGAAGAAAC
TCAACGCCCGACACAAGCAAACAGATGACTTTCGACAGGCGCTGTCTGCTGCGTTAACCAAGCTAATGTCGGAAGAGGAA
GTACACAATGACTTCAATATGGAAATGAGCCGTTTTATCCCTCAGAAAATTAAAGAAAGAACCATCGATAACTCAGAGTA
TTGGGCATACGTTCAGGGTGAGGTAACAGCCATCGCATCTGAGTTACTTGATGACGGCACACCCAAAAATCCATTTGATA
TGGGCTAG

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19430.69 Da        Isoelectric Point: 9.8751

>AT124755 WP_077659132.1 NZ_CP040021:161187-161711 [Salinivibrio kushneri]
MAKSDELLNVFAKAVRAGGGVHSAAELAFMLGVPCDPAFRKLLADSVKKGLLRRVVKGFYESMITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQIVMGRTTVVTKGRSGCFNTPYGVIEFTHTKRPVEKIAPNLYYDPDIQMYRAFKEQAIA
DLKHCRRNLHMLES

Download         Length: 525 bp

>AT124755 NZ_CP040021:161187-161711 [Salinivibrio kushneri]
ATGGCAAAGTCTGATGAGCTACTAAACGTATTCGCAAAAGCGGTTCGCGCTGGCGGAGGCGTTCACAGTGCAGCTGAGCT
TGCTTTTATGTTGGGTGTGCCCTGTGATCCTGCTTTTAGAAAACTCCTCGCAGATAGCGTAAAAAAGGGCTTGCTAAGAC
GGGTGGTAAAAGGGTTCTATGAAAGCATGATTACCCCTCCTGAGCCTGAGACGGCTATTTATAAAATCATCAAAAAGTTA
CGTAGTGGGGTATTGAATTACATCAGCTTGGAAAGCCAGCTCAGTCATACCGGTGATATTTCGCAAATTGTGATGGGCAG
GACCACGGTAGTGACTAAAGGTCGAAGTGGTTGTTTTAATACGCCTTATGGCGTGATCGAATTTACCCATACTAAAAGGC
CAGTCGAAAAAATCGCCCCTAATTTATACTATGACCCCGACATCCAAATGTATCGCGCATTCAAAGAACAAGCGATTGCA
GATCTAAAGCACTGCCGCCGCAATCTACATATGCTGGAGAGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References