Detailed information of TA system TA123447

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2794428..2795052
• Replicon: chromosome
• Accession: NZ_CP039031
• Organism: Acinetobacter indicus strain yy_1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9KY14
• Locus tag: E5093_RS13230
• Protein ID: WP_005180237.1
• Coordinates: 2794428..2794820 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: E5093_RS13235
• Protein ID: WP_171065118.1
• Coordinates: 2794807..2795052 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E5093_RS13210	2789753..2792029	-	2277	WP_168417097.1	TRAP transporter large permease subunit	-
E5093_RS13215	2792210..2792782	-	573	WP_177156069.1	rhombosortase	-
E5093_RS13220	2792838..2793911	-	1074	WP_005180236.1	hypothetical protein	-
E5093_RS13225	2794101..2794280	+	180	WP_127801044.1	hypothetical protein	-
E5093_RS13230	2794428..2794820	-	393	WP_005180237.1	hypothetical protein	Toxin
E5093_RS13235	2794807..2795052	-	246	WP_171065118.1	succinate dehydrogenase assembly factor 2	Antitoxin
E5093_RS13240	2795248..2796420	+	1173	WP_177156070.1	acyl-CoA dehydrogenase family protein	-
E5093_RS13245	2796508..2797998	-	1491	WP_005180241.1	NAD(P)/FAD-dependent oxidoreductase	-
E5093_RS13250	2798196..2798561	-	366	WP_004754212.1	50S ribosomal protein L17	-
E5093_RS13255	2798581..2799588	-	1008	WP_005180245.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14930.64 Da
• Isoelectric Point: 10.4540

>T123447 WP_005180237.1 NZ_CP039031:c2794820-2794428 [Acinetobacter indicus]
MSTAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGSK
IQRGLLEHILDHQLYLVLYFHHAPVKSAVIWRDQVSFAEWKALKTLAKTI

Nucleotide

• Length: 393 bp

>T123447 NZ_CP039031:c2794820-2794428 [Acinetobacter indicus]
ATGTCCACGGCTAAGCGCGACTTTCAGCTGAAACCGAGCCGTCTGGCGCTGCTGTTTCAGCTGAGCCTGCTGATTCTATT
TTCTGTTTTAAGTTTTCAATTATTACATCCGCTGCTTTGGCTGCTAGGTCTGCTCCTGGCGGCTGTCAGTTATTACGGGT
TTCAGCGACGTTCCCAATTAACCGCCTTGGCGCATTTAGATGGGGCAGAGTGGAGTCTGCAATTTAATTCTGGCTCCAAG
ATTCAACGCGGTCTGCTCGAGCATATTCTGGATCATCAGCTGTATCTGGTGCTGTATTTTCATCATGCACCGGTCAAATC
TGCAGTCATCTGGCGTGACCAAGTTTCGTTTGCAGAGTGGAAGGCCTTAAAAACATTGGCAAAAACCATCTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9758.15 Da
• Isoelectric Point: 4.9108

>AT123447 WP_171065118.1 NZ_CP039031:c2795052-2794807 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT123447 NZ_CP039031:c2795052-2794807 [Acinetobacter indicus]
ATTAGCTTAGAAGAGCGTAAAGTGATTTATCGTGCCCGTCGCGGTTTAAAGGAAATTGATGTCTACTTTGATCCTTATGT
AAAAAACTATTATTTAACCGCTGATCCGGAAGAAAAAGCCACGTTTGCTGCGCTGGTTGAACAGGAAGATCCGGATTTAC
TGGACTGGTTTATGGAAGTGTCTGAACCGCCACGCCCGGAAATGCGCGAGCTGATCCGTAAATTAAAACACTATGTCCAC
GGCTAA

Structures

Toxin

• AlphaFold DB: N9KY14