Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 22143..22786 | Replicon | plasmid unnamed3 |
| Accession | NZ_CP038911 | ||
| Organism | Piscirickettsia salmonis strain Psal-009 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | E9LHC6 |
| Locus tag | Psal009_RS18565 | Protein ID | WP_016210974.1 |
| Coordinates | 22143..22550 (-) | Length | 136 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | E9LHC5 |
| Locus tag | Psal009_RS18570 | Protein ID | WP_016210972.1 |
| Coordinates | 22559..22786 (-) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Psal009_RS18530 | 17389..17868 | - | 480 | WP_016212234.1 | P27 family phage terminase small subunit | - |
| Psal009_RS18535 | 17945..18337 | - | 393 | WP_155047322.1 | HNH endonuclease | - |
| Psal009_RS18540 | 18672..19646 | - | 975 | WP_054300271.1 | IS30 family transposase | - |
| Psal009_RS18545 | 19744..20061 | - | 318 | WP_129556723.1 | hypothetical protein | - |
| Psal009_RS18550 | 20262..20591 | - | 330 | WP_036780870.1 | hypothetical protein | - |
| Psal009_RS18555 | 20591..20917 | - | 327 | WP_155047323.1 | zinc ribbon domain-containing protein | - |
| Psal009_RS18560 | 21346..22131 | - | 786 | WP_155047324.1 | DNA/RNA non-specific endonuclease | - |
| Psal009_RS18565 | 22143..22550 | - | 408 | WP_016210974.1 | DUF4411 family protein | Toxin |
| Psal009_RS18570 | 22559..22786 | - | 228 | WP_016210972.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| Psal009_RS18575 | 23082..24056 | + | 975 | WP_054300271.1 | IS30 family transposase | - |
| Psal009_RS18580 | 24076..24405 | - | 330 | WP_155047330.1 | hypothetical protein | - |
| Psal009_RS18585 | 24547..25020 | - | 474 | WP_016210960.1 | single-stranded DNA-binding protein | - |
| Psal009_RS18590 | 25022..25282 | - | 261 | WP_016210965.1 | hypothetical protein | - |
| Psal009_RS18595 | 25303..25692 | - | 390 | WP_036780969.1 | hypothetical protein | - |
| Psal009_RS18600 | 25685..25924 | - | 240 | WP_155047325.1 | hypothetical protein | - |
| Psal009_RS18605 | 25921..26268 | - | 348 | WP_155047331.1 | hypothetical protein | - |
| Psal009_RS18610 | 26261..26623 | - | 363 | WP_016210959.1 | hypothetical protein | - |
| Psal009_RS18615 | 26592..27152 | - | 561 | WP_016210973.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..38376 | 38376 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 15625.00 Da Isoelectric Point: 7.4170
>T123359 WP_016210974.1 NZ_CP038911:c22550-22143 [Piscirickettsia salmonis]
MLYMLDTNICIYLIKQKPRSYYERLMEVEKSRHILAISSIVLSELQFGVARSQHQRKNQEAINTLVNKLEVLPYEEKAAK
YYGDLRADLQKKGTVIGGNDMIIAAHALSEKAVLVTHNTKEFQRVEHLEFEDWAS
MLYMLDTNICIYLIKQKPRSYYERLMEVEKSRHILAISSIVLSELQFGVARSQHQRKNQEAINTLVNKLEVLPYEEKAAK
YYGDLRADLQKKGTVIGGNDMIIAAHALSEKAVLVTHNTKEFQRVEHLEFEDWAS
Download Length: 408 bp
>T123359 NZ_CP038911:c22550-22143 [Piscirickettsia salmonis]
ATGCTTTATATGCTGGATACGAATATTTGTATTTATTTAATTAAACAAAAGCCTCGTTCTTACTATGAGCGTTTGATGGA
GGTAGAAAAATCTCGTCATATATTGGCGATTTCATCCATTGTTTTATCTGAATTACAGTTTGGAGTGGCTCGGAGTCAAC
ACCAGCGAAAAAACCAGGAAGCGATTAATACCTTGGTAAATAAGCTAGAAGTTTTACCCTATGAGGAAAAGGCAGCTAAA
TACTATGGTGACTTAAGGGCTGACTTACAAAAAAAAGGGACTGTGATTGGTGGGAATGATATGATCATAGCCGCGCATGC
GCTCTCAGAAAAAGCCGTTTTAGTGACACATAATACAAAAGAGTTTCAGCGTGTCGAGCATTTAGAGTTTGAAGACTGGG
CAAGTTAA
ATGCTTTATATGCTGGATACGAATATTTGTATTTATTTAATTAAACAAAAGCCTCGTTCTTACTATGAGCGTTTGATGGA
GGTAGAAAAATCTCGTCATATATTGGCGATTTCATCCATTGTTTTATCTGAATTACAGTTTGGAGTGGCTCGGAGTCAAC
ACCAGCGAAAAAACCAGGAAGCGATTAATACCTTGGTAAATAAGCTAGAAGTTTTACCCTATGAGGAAAAGGCAGCTAAA
TACTATGGTGACTTAAGGGCTGACTTACAAAAAAAAGGGACTGTGATTGGTGGGAATGATATGATCATAGCCGCGCATGC
GCTCTCAGAAAAAGCCGTTTTAGTGACACATAATACAAAAGAGTTTCAGCGTGTCGAGCATTTAGAGTTTGAAGACTGGG
CAAGTTAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8929.02 Da Isoelectric Point: 4.5679
>AT123359 WP_016210972.1 NZ_CP038911:c22786-22559 [Piscirickettsia salmonis]
MAKSRIFKSGNSQAVRLPKEMRLDGEEVVIHRFGNSLLIQPVYETWMDVYNHMPDVSDDFMEDHQDIQAQERDWF
MAKSRIFKSGNSQAVRLPKEMRLDGEEVVIHRFGNSLLIQPVYETWMDVYNHMPDVSDDFMEDHQDIQAQERDWF
Download Length: 228 bp
>AT123359 NZ_CP038911:c22786-22559 [Piscirickettsia salmonis]
ATGGCAAAATCACGAATTTTTAAAAGTGGTAATTCCCAAGCCGTTCGGTTACCGAAAGAAATGCGGCTGGATGGTGAAGA
AGTGGTTATTCATCGGTTTGGCAACTCTTTATTAATCCAGCCAGTTTATGAAACCTGGATGGATGTTTACAATCATATGC
CGGATGTATCGGATGATTTTATGGAAGATCATCAAGATATACAAGCACAAGAACGTGACTGGTTTTAG
ATGGCAAAATCACGAATTTTTAAAAGTGGTAATTCCCAAGCCGTTCGGTTACCGAAAGAAATGCGGCTGGATGGTGAAGA
AGTGGTTATTCATCGGTTTGGCAACTCTTTATTAATCCAGCCAGTTTATGAAACCTGGATGGATGTTTACAATCATATGC
CGGATGTATCGGATGATTTTATGGAAGATCATCAAGATATACAAGCACAAGAACGTGACTGGTTTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|