Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2378166..2378820 Replicon chromosome
Accession NZ_CP038438
Organism Pseudomonas fluorescens strain LBUM677

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag E4T63_RS10670 Protein ID WP_135296915.1
Coordinates 2378470..2378820 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag E4T63_RS10665 Protein ID WP_027614657.1
Coordinates 2378166..2378480 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4T63_RS10630 2374011..2374211 + 201 WP_098968143.1 hypothetical protein -
E4T63_RS10635 2374278..2374610 + 333 WP_135295437.1 DUF2790 domain-containing protein -
E4T63_RS10645 2375068..2375448 + 381 WP_095138906.1 hypothetical protein -
E4T63_RS10650 2375738..2376028 + 291 WP_041073246.1 DUF1778 domain-containing protein -
E4T63_RS10655 2375986..2376507 + 522 WP_135295438.1 hypothetical protein -
E4T63_RS10660 2376667..2377992 - 1326 WP_135295439.1 OprD family porin -
E4T63_RS10665 2378166..2378480 - 315 WP_027614657.1 transcriptional regulator Antitoxin
E4T63_RS10670 2378470..2378820 - 351 WP_135296915.1 toxin Toxin
E4T63_RS10675 2379190..2379654 + 465 WP_135295440.1 GNAT family N-acetyltransferase -
E4T63_RS10680 2379846..2381309 - 1464 WP_003223784.1 NADH-quinone oxidoreductase subunit NuoN -
E4T63_RS10685 2381317..2382849 - 1533 WP_003223785.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13976.80 Da        Isoelectric Point: 7.2031

>T122792 WP_135296915.1 NZ_CP038438:c2378820-2378470 [Pseudomonas fluorescens]
MDALFIELPVFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEDTGGLRKIRFSDQRRGKGKRSGLRVIYYWWPGFDQFWL
FTVFNKNEQDDLTPAQKKLFRKTLDRELNARSHYET

Download         Length: 351 bp

>T122792 NZ_CP038438:c2378820-2378470 [Pseudomonas fluorescens]
ATGGATGCTCTATTTATCGAATTGCCTGTGTTTCAGAAGCACCGAGACGACTATCTGGATGACGATCTGTTTCGCAGCTT
TCAATTGGAGTTGCTGAAAAATCCGGAAGCGGGCGATCTCATCGAGGACACAGGCGGGCTTCGTAAAATTCGCTTCAGCG
ACCAACGAAGAGGGAAAGGCAAGCGCAGCGGATTACGAGTGATTTATTACTGGTGGCCAGGCTTCGATCAGTTCTGGCTC
TTTACCGTCTTCAACAAAAACGAGCAGGACGATTTGACGCCTGCCCAGAAAAAGCTTTTCAGAAAAACACTGGATAGAGA
ACTCAACGCGAGAAGCCACTATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11950.86 Da        Isoelectric Point: 9.9896

>AT122792 WP_027614657.1 NZ_CP038438:c2378480-2378166 [Pseudomonas fluorescens]
MKRDIFSELMDGLEALADERQGKITLRTHKVQLPKLMPITAEEVIAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp

>AT122792 NZ_CP038438:c2378480-2378166 [Pseudomonas fluorescens]
ATGAAACGTGACATTTTTTCCGAACTGATGGATGGACTGGAAGCACTGGCCGATGAACGCCAAGGCAAAATCACCTTGCG
TACCCATAAGGTTCAGCTGCCAAAACTGATGCCGATCACTGCTGAGGAAGTGATAGCCATCCGTCAGCAACTTAATCTTT
CCCGGTCAGTTTTCGCGATGTATCTACGCACCAATACGCGAACGCTCGAGAACTGGGAGCAAGGACGAGCTACGCCCAAT
GCTCAGGCCACAACCCTGATCCGTCTGGTCGAGCGTTTTCCACAGACAATCGAACAACTCGCAGCCCTGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References