Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2237623..2237857 | Replicon | chromosome |
| Accession | NZ_CP038394 | ||
| Organism | Escherichia coli O157:H7 strain DEC5A | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2237753..2237856 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2237623..2237857 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E3155_RS10875 | 2234178..2234840 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| E3155_RS10880 | 2234864..2235520 | - | 657 | WP_000011661.1 | carbon-nitrogen hydrolase family protein | - |
| E3155_RS10885 | 2235622..2235852 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| E3155_RS10890 | 2235991..2236365 | + | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| E3155_RS10895 | 2236369..2237241 | + | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| E3155_RS10900 | 2237254..2237595 | + | 342 | WP_000976483.1 | YebY family protein | - |
| - | 2237623..2237857 | - | 235 | - | - | Antitoxin |
| - | 2237753..2237856 | + | 104 | - | - | Toxin |
| E3155_RS10905 | 2237988..2239064 | - | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| E3155_RS10910 | 2239030..2239311 | - | 282 | WP_001311878.1 | excisionase | - |
| E3155_RS10915 | 2239418..2239606 | - | 189 | WP_001417978.1 | DUF1187 family protein | - |
| - | 2239422..2239600 | + | 179 | NuclAT_1 | - | - |
| - | 2239422..2239600 | + | 179 | NuclAT_1 | - | - |
| - | 2239422..2239600 | + | 179 | NuclAT_1 | - | - |
| - | 2239422..2239600 | + | 179 | NuclAT_1 | - | - |
| E3155_RS10920 | 2239599..2239793 | - | 195 | WP_071780718.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| E3155_RS10925 | 2239857..2240909 | - | 1053 | WP_001004419.1 | recombinase RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2232121..2296436 | 64315 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T122325 NZ_CP038394:2237753-2237856 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT122325 NZ_CP038394:c2237857-2237623 [Escherichia coli O157:H7]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
