Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2235365..2235636 Replicon chromosome
Accession NZ_CP038372
Organism Escherichia coli O157:H7 strain F6294

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2235495..2235598 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2235365..2235636 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3161_RS11115 2231920..2232582 - 663 WP_000944243.1 exodeoxyribonuclease X -
E3161_RS11120 2232606..2233262 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
E3161_RS11125 2233364..2233594 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3161_RS11130 2233733..2234107 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3161_RS11135 2234111..2234983 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3161_RS11140 2234996..2235337 + 342 WP_000976483.1 YebY family protein -
- 2235365..2235636 - 272 - - Antitoxin
- 2235495..2235598 + 104 - - Toxin
E3161_RS11145 2235733..2236389 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3161_RS11150 2236390..2236581 - 192 WP_001296140.1 YebW family protein -
E3161_RS11155 2236686..2236922 - 237 WP_001295499.1 DUF1480 family protein -
E3161_RS11160 2237040..2238479 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T122089 NZ_CP038372:2235495-2235598 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT122089 NZ_CP038372:c2235636-2235365 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References