Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3075562..3077054 Replicon chromosome
Accession NZ_CP036281
Organism Polystyrenella longa strain Pla110

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag Pla110_RS11440 Protein ID WP_144995894.1
Coordinates 3076161..3077054 (+) Length 298 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag Pla110_RS11435 Protein ID WP_144995893.1
Coordinates 3075562..3076164 (+) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pla110_RS11410 3070875..3071540 - 666 WP_197440144.1 sigma-70 family RNA polymerase sigma factor -
Pla110_RS11415 3071640..3072398 - 759 WP_144995889.1 Rrf2 family transcriptional regulator -
Pla110_RS11420 3072753..3073256 + 504 WP_144995890.1 DUF2924 domain-containing protein -
Pla110_RS11425 3073253..3074797 + 1545 WP_144995891.1 recombinase family protein -
Pla110_RS11430 3074794..3075198 + 405 WP_144995892.1 hypothetical protein -
Pla110_RS11435 3075562..3076164 + 603 WP_144995893.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
Pla110_RS11440 3076161..3077054 + 894 WP_144995894.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Pla110_RS11445 3077097..3077291 - 195 WP_144995895.1 hypothetical protein -
Pla110_RS11455 3077909..3078334 - 426 WP_144995896.1 ATP-binding protein -
Pla110_RS11460 3078596..3078955 - 360 WP_144995897.1 STAS domain-containing protein -
Pla110_RS11465 3079522..3081336 - 1815 WP_144995898.1 translational GTPase TypA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-51)


Sequences

Toxin        


Download         Length: 298 a.a.        Molecular weight: 34351.11 Da        Isoelectric Point: 5.1449

>T119467 WP_144995894.1 NZ_CP036281:3076161-3077054 [Polystyrenella longa]
MTKNIAASVRQKLLNISRERKQRFNELLLRYALERWLYRLSQSRYSEKFVLKGAMMLTAWQIPTTRPTRDIDMLAQISND
LDAVLGVIIEINQTETEPDGLIFDTENIITERIAEDALYEGVRARFRGNLDSARLDMQIDIGFSDIVTPGPVDMTFPTIL
DQPAPQLNAYNPETAIAEKFEAMVKLGELNSRMKDFYDIWALSQFHSFTKSLLDKAVRSTFRRRDTELDTNASCFSKEYG
TSENKQKQWQAFLKRSQLNEVAPANFEDVWKATIKFLEPIIHPQEDELKWEAGGPWK

Download         Length: 894 bp

>T119467 NZ_CP036281:3076161-3077054 [Polystyrenella longa]
ATGACCAAAAACATCGCAGCCTCTGTACGACAGAAACTTTTAAACATTTCCCGCGAAAGGAAGCAACGTTTCAACGAACT
CCTCTTACGATATGCTCTGGAGCGGTGGCTCTACCGGTTATCCCAAAGTCGCTATTCAGAGAAGTTCGTGTTGAAAGGAG
CCATGATGCTGACAGCATGGCAAATACCGACGACACGCCCAACCAGAGACATCGATATGCTCGCCCAAATATCCAACGAC
TTGGATGCCGTACTAGGAGTGATCATAGAAATCAATCAGACTGAGACGGAACCCGATGGATTGATTTTTGATACCGAGAA
CATAATAACGGAGCGAATCGCCGAAGACGCGTTGTACGAAGGAGTGCGCGCCCGATTTCGAGGCAATCTGGATTCCGCGC
GACTGGATATGCAAATCGACATTGGATTCAGTGACATTGTTACTCCCGGGCCGGTGGATATGACCTTTCCAACGATTTTG
GACCAACCCGCTCCCCAACTGAATGCCTACAACCCAGAGACCGCCATCGCGGAGAAATTTGAAGCGATGGTCAAGTTAGG
AGAACTCAACAGTCGAATGAAAGATTTCTATGACATATGGGCACTGTCACAATTCCATTCATTCACTAAATCGTTGCTCG
ATAAAGCAGTCCGGTCCACTTTCCGACGCCGGGACACAGAACTGGATACGAATGCATCGTGCTTCTCTAAAGAGTATGGC
ACATCTGAAAACAAGCAGAAGCAATGGCAGGCATTTTTGAAGCGAAGCCAACTGAACGAGGTCGCTCCCGCAAATTTTGA
AGATGTTTGGAAAGCTACGATCAAATTCCTAGAGCCGATTATTCACCCGCAAGAGGACGAACTAAAATGGGAGGCAGGTG
GCCCCTGGAAATAA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22780.55 Da        Isoelectric Point: 9.9610

>AT119467 WP_144995893.1 NZ_CP036281:3075562-3076164 [Polystyrenella longa]
MQKTSKKALKIISKKGGIIRTREALEYGIHPRTLYSLRDQGDLEIISRGLYKLSSLPPVGDPDLELVAGRIPQGIVCLIS
ALAIHELTTQIPHEVHLAIPRTARYPVCHEVPIKIYRFSDLAYKSGIIQKEIDGFKVKVYDSEKTLADTFKYRNKIGLDV
FLEALNNYQRRKDSSLQKVLEYAKIDRVSKQIRPYLEATT

Download         Length: 603 bp

>AT119467 NZ_CP036281:3075562-3076164 [Polystyrenella longa]
ATGCAGAAAACAAGTAAAAAAGCACTAAAAATAATATCAAAAAAAGGAGGAATAATTCGGACGAGAGAGGCTCTCGAATA
CGGAATTCACCCACGAACCCTCTATTCGCTACGAGACCAAGGCGACCTCGAAATCATTTCGCGAGGACTGTACAAACTGT
CGTCTCTACCGCCTGTAGGTGACCCGGATCTGGAACTGGTGGCCGGACGCATTCCCCAAGGCATCGTATGCCTAATATCC
GCACTTGCGATCCATGAACTCACCACGCAGATACCGCACGAAGTTCATCTCGCCATCCCAAGGACGGCACGATATCCCGT
CTGTCATGAAGTCCCCATAAAGATCTATCGATTTTCCGATCTCGCATACAAATCGGGAATCATCCAAAAAGAAATCGATG
GCTTCAAGGTTAAGGTCTATGACTCGGAGAAGACCCTCGCGGATACATTCAAGTATCGGAATAAAATCGGGCTCGACGTC
TTCCTCGAGGCACTCAACAACTACCAGAGACGTAAAGATTCTTCACTGCAGAAGGTACTGGAATACGCCAAAATCGATAG
GGTTTCGAAACAGATCCGTCCATATCTGGAGGCCACAACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References