Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2410765..2411036 Replicon chromosome
Accession NZ_CP035874
Organism Escherichia coli strain B2C

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2410895..2410998 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2410765..2411036 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW998_RS11545 2407320..2407982 - 663 WP_000944258.1 exodeoxyribonuclease X -
EW998_RS11550 2408006..2408662 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EW998_RS11555 2408764..2408994 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EW998_RS11560 2409133..2409507 + 375 WP_000168746.1 CopC domain-containing protein YobA -
EW998_RS11565 2409511..2410383 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EW998_RS11570 2410396..2410737 + 342 WP_000976472.1 YebY family protein -
- 2410765..2411036 - 272 - - Antitoxin
- 2410895..2410998 + 104 - - Toxin
EW998_RS11575 2411133..2411789 + 657 WP_000812772.1 protein-serine/threonine phosphatase -
EW998_RS11580 2411790..2411981 - 192 WP_001338167.1 YebW family protein -
EW998_RS11585 2412086..2412322 - 237 WP_001338166.1 YebV family protein -
EW998_RS11590 2412440..2413879 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118942 NZ_CP035874:2410895-2410998 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118942 NZ_CP035874:c2411036-2410765 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References