Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2239773..2240044 Replicon chromosome
Accession NZ_CP035832
Organism Escherichia coli strain 025542-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2239903..2240006 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2239773..2240044 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA04_RS10965 2236328..2236990 - 663 WP_000944256.1 exodeoxyribonuclease X -
EXA04_RS10970 2237014..2237670 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
EXA04_RS10975 2237772..2238002 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EXA04_RS10980 2238141..2238515 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EXA04_RS10985 2238519..2239391 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
EXA04_RS10990 2239404..2239745 + 342 WP_000976492.1 YebY family protein -
- 2239773..2240044 - 272 - - Antitoxin
- 2239903..2240006 + 104 - - Toxin
EXA04_RS10995 2240141..2240797 + 657 WP_000812723.1 protein-serine/threonine phosphatase -
EXA04_RS11000 2240798..2240989 - 192 WP_001338167.1 YebW family protein -
EXA04_RS11005 2241094..2241330 - 237 WP_001295499.1 YebV family protein -
EXA04_RS11010 2241448..2242887 - 1440 WP_001352399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2168356..2255884 87528


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118683 NZ_CP035832:2239903-2240006 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTTCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118683 NZ_CP035832:c2240044-2239773 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGAAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References