Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2488661..2488932 Replicon chromosome
Accession NZ_CP035751
Organism Escherichia coli E110019

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2488699..2488802 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2488661..2488932 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECE110019_RS12310 2485818..2487257 + 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECE110019_RS12315 2487375..2487611 + 237 WP_001295499.1 DUF1480 family protein -
ECE110019_RS12320 2487716..2487907 + 192 WP_001296140.1 YebW family protein -
ECE110019_RS12325 2487908..2488564 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2488661..2488932 + 272 - - Antitoxin
- 2488699..2488802 - 104 - - Toxin
ECE110019_RS12330 2488960..2489301 - 342 WP_000976472.1 YebY family protein -
ECE110019_RS12335 2489314..2490186 - 873 WP_000879305.1 copper homeostasis membrane protein CopD -
ECE110019_RS12340 2490190..2490564 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECE110019_RS12345 2490703..2490933 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECE110019_RS12350 2491035..2491691 + 657 WP_000011668.1 carbon-nitrogen hydrolase family protein -
ECE110019_RS12355 2491715..2492377 + 663 Protein_2429 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T118380 NZ_CP035751:c2488802-2488699 [Escherichia coli E110019]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT118380 NZ_CP035751:2488661-2488932 [Escherichia coli E110019]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References