Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 676928..677535 Replicon chromosome
Accession NZ_CP035495
Organism Xylanimonas allomyrinae strain 2JSPR-7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag ET495_RS03035 Protein ID WP_129202498.1
Coordinates 677182..677535 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag ET495_RS03030 Protein ID WP_129202496.1
Coordinates 676928..677185 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ET495_RS03000 671929..673239 + 1311 WP_129202490.1 cysteine desulfurase -
ET495_RS03005 673250..673729 + 480 WP_129202491.1 SUF system NifU family Fe-S cluster assembly protein -
ET495_RS03010 673741..674076 + 336 WP_129202492.1 metal-sulfur cluster assembly factor -
ET495_RS03015 674670..674858 - 189 WP_129202493.1 hypothetical protein -
ET495_RS03020 675387..675812 + 426 WP_129205857.1 hypothetical protein -
ET495_RS03025 675805..676629 + 825 WP_162616343.1 zeta toxin family protein -
ET495_RS03030 676928..677185 + 258 WP_129202496.1 antitoxin Antitoxin
ET495_RS03035 677182..677535 + 354 WP_129202498.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
ET495_RS03040 678087..678908 + 822 WP_129202500.1 ABC transporter ATP-binding protein -
ET495_RS03045 678986..680005 + 1020 WP_129202502.1 iron-siderophore ABC transporter substrate-binding protein -
ET495_RS03050 680010..682133 + 2124 WP_129202504.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12472.11 Da        Isoelectric Point: 7.3618

>T117982 WP_129202498.1 NZ_CP035495:677182-677535 [Xylanimonas allomyrinae]
MRRGEVWAVELDPARGSEASKTRRCVIVSRDASNKAVETHGRGVVTVVPLTSSVARVLPFQALVPAEPGNGLDHDSKAQA
EQVRSVDVSRLVARVGTLRSEHVGAVDDALITHLGLD

Download         Length: 354 bp

>T117982 NZ_CP035495:677182-677535 [Xylanimonas allomyrinae]
ATGAGGCGTGGCGAGGTCTGGGCGGTCGAGCTTGACCCTGCGCGAGGCTCGGAGGCATCCAAGACAAGGCGGTGCGTGAT
CGTCTCTCGCGACGCGAGCAACAAGGCCGTCGAGACGCACGGGAGGGGTGTCGTCACGGTGGTTCCGTTGACGTCGTCCG
TTGCTCGAGTTCTTCCCTTCCAGGCGCTCGTCCCTGCGGAGCCAGGAAACGGACTCGACCACGACTCGAAGGCTCAGGCC
GAACAGGTCCGCTCCGTGGATGTGTCGCGGCTGGTGGCCCGCGTCGGGACGCTTCGCTCCGAGCATGTGGGTGCGGTGGA
CGACGCGCTGATCACTCACCTGGGCCTGGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9382.46 Da        Isoelectric Point: 5.1373

>AT117982 WP_129202496.1 NZ_CP035495:676928-677185 [Xylanimonas allomyrinae]
MTVGARDRGTVKLSASLPAADVAYLERYARRHRLPSRSATLHAAVQALRERELEAQYAEAYREWEESGEAAVWDVAVADG
IEPVA

Download         Length: 258 bp

>AT117982 NZ_CP035495:676928-677185 [Xylanimonas allomyrinae]
ATGACCGTTGGTGCGAGGGACCGTGGGACCGTCAAGCTCAGTGCAAGCCTGCCGGCCGCAGACGTGGCGTACCTGGAGCG
CTACGCAAGGCGCCACCGGCTGCCCTCGCGATCGGCCACACTGCACGCCGCGGTGCAGGCCCTTCGCGAACGCGAGCTCG
AAGCGCAGTACGCGGAGGCGTATCGCGAGTGGGAGGAGTCCGGAGAGGCGGCGGTGTGGGACGTGGCGGTTGCCGACGGG
ATCGAGCCGGTCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References