Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1884753..1885413 Replicon chromosome
Accession NZ_CP035034
Organism Pantoea ananatis strain NN08200

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EPK90_RS08955 Protein ID WP_128391965.1
Coordinates 1884753..1885106 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EPK90_RS08960 Protein ID WP_128391966.1
Coordinates 1885111..1885413 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPK90_RS08935 1880591..1882072 + 1482 WP_128391964.1 rhamnulokinase -
EPK90_RS08940 1882056..1883312 + 1257 WP_105076819.1 L-rhamnose isomerase -
EPK90_RS08945 1883323..1884165 + 843 WP_015699976.1 rhamnulose-1-phosphate aldolase -
EPK90_RS08950 1884155..1884469 + 315 WP_015699977.1 L-rhamnose mutarotase -
EPK90_RS08955 1884753..1885106 + 354 WP_128391965.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EPK90_RS08960 1885111..1885413 + 303 WP_128391966.1 XRE family transcriptional regulator Antitoxin
EPK90_RS08970 1886332..1887453 + 1122 WP_128391967.1 Gfo/Idh/MocA family oxidoreductase -
EPK90_RS08975 1887533..1888360 - 828 WP_128391968.1 glycosyltransferase family 8 protein -
EPK90_RS08980 1888362..1889759 - 1398 WP_128391969.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-81)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13377.35 Da        Isoelectric Point: 9.5793

>T117139 WP_128391965.1 NZ_CP035034:1884753-1885106 [Pantoea ananatis]
VWPIKTTDTFDCWFTSLSDIDRADMLAALLVLREKGPGLSRPYADTLKGSRYSNMKERRIQSRGDPLRAFFAFDPARTGI
VLCAGNKVGNEKRFYDAMLPVADREFTNWLNVLKNKE

Download         Length: 354 bp

>T117139 NZ_CP035034:1884753-1885106 [Pantoea ananatis]
GTGTGGCCGATTAAAACAACGGATACGTTTGACTGCTGGTTTACCTCGCTTAGCGATATCGACAGGGCTGACATGCTTGC
AGCATTGTTGGTCCTGCGGGAGAAGGGGCCGGGTTTGTCCAGACCTTATGCCGATACGCTCAAAGGCTCCCGCTATAGCA
ACATGAAAGAACGACGTATCCAGAGCCGGGGCGATCCTTTACGGGCATTTTTTGCCTTTGACCCGGCCCGAACCGGCATT
GTGCTTTGTGCTGGAAATAAGGTCGGCAATGAAAAACGTTTTTACGACGCGATGCTCCCGGTTGCTGACCGGGAATTTAC
GAACTGGCTTAACGTATTAAAAAATAAGGAGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10985.73 Da        Isoelectric Point: 5.7251

>AT117139 WP_128391966.1 NZ_CP035034:1885111-1885413 [Pantoea ananatis]
MGRTLEQLIAEEKNDVVADAQAMATDILLNIHLAELREKVQKTQIEMAQALGIKQPGVAGMEKPGRDLKLSTLKRYVEAT
GGKLRLDVELPDGSHYGFVL

Download         Length: 303 bp

>AT117139 NZ_CP035034:1885111-1885413 [Pantoea ananatis]
ATGGGTAGAACGCTGGAACAGCTTATTGCGGAGGAAAAAAATGACGTCGTGGCTGACGCTCAGGCGATGGCGACGGACAT
CCTGCTCAATATTCACCTTGCCGAACTGCGTGAGAAAGTACAAAAAACGCAGATAGAAATGGCGCAGGCGCTGGGCATCA
AACAACCTGGCGTTGCAGGAATGGAAAAACCGGGGCGCGACCTGAAGCTGTCCACGCTCAAACGCTATGTTGAAGCGACC
GGTGGCAAGCTTCGCCTTGATGTTGAACTGCCGGATGGTTCTCACTACGGTTTTGTGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References