Detailed information of TA system TA117005

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 4742210..4743651
• Replicon: chromosome
• Accession: NZ_CP034938
• Organism: Pectobacterium odoriferum strain JK2.1

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: EO763_RS21385
• Protein ID: WP_161530141.1
• Coordinates: 4742210..4743097 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: A0A7T5UAJ1
• Locus tag: EO763_RS21390
• Protein ID: WP_039490190.1
• Coordinates: 4743127..4743651 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EO763_RS21365	4738202..4739023	+	822	WP_161530139.1	M55 family metallopeptidase	-
EO763_RS21370	4739084..4740031	+	948	WP_039490183.1	isoaspartyl peptidase/L-asparaginase	-
EO763_RS21375	4740236..4741144	+	909	WP_103162628.1	LysR family transcriptional regulator	-
EO763_RS21380	4741242..4742105	+	864	WP_161530140.1	YicC family protein	-
EO763_RS21385	4742210..4743097	-	888	WP_161530141.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EO763_RS21390	4743127..4743651	-	525	WP_039490190.1	hypothetical protein	Antitoxin
EO763_RS21400	4745286..4747775	-	2490	WP_161530142.1	restriction endonuclease-like protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34044.93 Da
• Isoelectric Point: 5.2750

>T117005 WP_161530141.1 NZ_CP034938:c4743097-4742210 [Pectobacterium odoriferum]
MLKQQIRQIIQSNPDYVAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVNAIASELLNDGTTKNPFDMG

Nucleotide

• Length: 888 bp

>T117005 NZ_CP034938:c4743097-4742210 [Pectobacterium odoriferum]
ATGCTGAAGCAACAAATTCGCCAAATCATCCAGTCAAACCCTGACTATGTCGCAGTAACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATCGATGTGCTGATCAAACAGGGCGTCATGCAGCGGTTAACGTTTATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGCAGCAGGCTATCAGAAGATCTTGATTTCAATGGTGGTCATGATTTCCAGCCCTCAGCGTTTGAG
GGGCTGGAGTCCGAAATTCAAACCTATATTCAGAACAAGTATGAAACCGAAGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACCGTTTCTTGGAAAATTAGTATCGTAAAAGAAGCTAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGACGTCTGTGCTATTCCGTCATTTGATATTGAAAAGCGCCCGCTAATCAATCATTACGACATCGTTGTACCGACTGAA
GGGATTTTGGTTCCGGTACAGTCGTTACAAGAAACATTGGCCGATAAGTTGATCGCGTTAGCGTATCGGGCAAGGCGTAT
TAAACCTCGTGATATCTGGGATATCGTTTGGATTAAGCAGCGCGGTATTGATTTATCCAAGACACTGGTTGAAAAGAAGC
TCACCGCCAGACAGAAGCAAACAGAAGACTTTCGACAGGCACTGTCTATTCAGTTAGCCAAGCTGATGTCGGAAGATGAA
GTCCGTGACGACTTCAATATGGAAATGAGCCGCTTTATTCCTAAGCAAATTAAAGAGAGAACCCTCGATAATCCTGAATA
TTGGGCTTATGTTCAGGGCGAGGTAAATGCCATCGCGTCTGAGTTATTGAATGACGGAACAACAAAAAATCCATTTGATA
TGGGTTAG

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19358.53 Da
• Isoelectric Point: 9.0504

>AT117005 WP_039490190.1 NZ_CP034938:c4743651-4743127 [Pectobacterium odoriferum]
MAKSDELLNALAKSVNAGGGIHSVTELAFMQGVPCDPAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT117005 NZ_CP034938:c4743651-4743127 [Pectobacterium odoriferum]
ATGGCTAAATCTGATGAGCTATTAAACGCGTTGGCTAAATCAGTGAACGCTGGCGGTGGCATTCACAGTGTAACAGAGCT
GGCTTTTATGCAGGGTGTGCCTTGTGACCCAGCCTTTAGAAAGTTCCTGGCAGATTGCGTAAAGAAGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGTGGCGTATTGAACTACATCAGCTTAGAAAGTCAGCTCAGTCATACTGGTGATATTTCACAAGTTGTGATGGGTAG
GGTCACGGTGGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATCGAGCTTACCCATACTAAAAAGC
CAGTCGAGCAAATTGCACCTAATTTGTACTATGACCCTGACATCAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAGCACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA

Structures

Antitoxin

• AlphaFold DB: A0A7T5UAJ1