Detailed information of TA system TA116872

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3065978..3066380
• Replicon: chromosome
• Accession: NZ_CP034819
• Organism: Salmonella sp. SSDFZ54

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A8E5MY29
• Locus tag: EOS97_RS15140
• Protein ID: WP_000994214.1
• Coordinates: 3065978..3066223 (-)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3066092..3066380 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EOS97_RS15125	3064463..3065160	+	698	Protein_2832	IS1 family transposase	-
EOS97_RS15130	3065162..3065506	+	345	WP_206613216.1	hypothetical protein	-
EOS97_RS15135	3065481..3065906	+	426	WP_001805083.1	hypothetical protein	-
EOS97_RS15140	3065978..3066223	-	246	WP_000994214.1	hypothetical protein	Toxin
-	3066092..3066380	+	289	-	-	Antitoxin
EOS97_RS26945	3067360..3067666	+	307	Protein_2836	hypothetical protein	-
EOS97_RS15150	3067663..3068130	+	468	WP_000828174.1	exported pathogenicity island protein	-
EOS97_RS15160	3068447..3068725	+	279	WP_077906530.1	hypothetical protein	-
EOS97_RS15165	3068792..3069067	-	276	WP_071785296.1	type I toxin-antitoxin system SymE family toxin	-
EOS97_RS15170	3069131..3069286	+	156	Protein_2840	transposase	-
EOS97_RS15175	3069357..3070043	-	687	Protein_2841	IS21-like element helper ATPase IstB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3042057..3079944	37887
	-	inside	IScluster/Tn	-	-	3064463..3069734	5271

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8763.81 Da
• Isoelectric Point: 4.5124

>T116872 WP_000994214.1 NZ_CP034819:c3066223-3065978 [Salmonella sp. SSDFZ54]
MNASGASVRHINSETCMTACYSQIPSGDSQEEAGFETGRSVTVKVSEGCLTIIADNNEVQELREQLYQAKQVVKGVKEVL
V

Nucleotide

• Length: 246 bp

>T116872 NZ_CP034819:c3066223-3065978 [Salmonella sp. SSDFZ54]
ATGAATGCCTCCGGCGCCAGCGTCCGCCACATCAACAGCGAAACCTGCATGACCGCCTGTTACTCACAAATCCCCAGCGG
CGACAGCCAGGAAGAAGCGGGATTTGAGACCGGGCGCAGCGTGACCGTGAAGGTTTCGGAAGGATGCCTGACCATCATCG
CTGACAATAACGAGGTGCAGGAGTTGCGGGAACAGCTTTATCAAGCTAAACAGGTAGTTAAAGGGGTGAAGGAAGTGCTT
GTTTAG

Antitoxin

Nucleotide

• Length: 289 bp

>AT116872 NZ_CP034819:3066092-3066380 [Salmonella sp. SSDFZ54]
CTTCACGGTCACGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGGCTGTCGCCGCTGGGGATTTGTGAGTAACAGGCGG
TCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTC
TCCGCCGGATGCTGGCTGATTGTGGAGCTTAGGGTGAGCGAGTATGGGCGCGACATCATGGCACCGCGCCTCCCTCTCCC
CGGCCAGCACCGGGCGGTGATGAGCAACCGGCTGCCGGGGCCGTATTTT

Structures

Antitoxin