Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1103159..1103430 Replicon chromosome
Accession NZ_CP034738
Organism Escherichia coli strain L65

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1103197..1103300 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1103159..1103430 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EM854_RS05450 1100316..1101755 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EM854_RS05455 1101873..1102109 + 237 WP_001295499.1 DUF1480 family protein -
EM854_RS05460 1102214..1102405 + 192 WP_001296140.1 YebW family protein -
EM854_RS05465 1102406..1103062 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1103159..1103430 + 272 - - Antitoxin
- 1103197..1103300 - 104 - - Toxin
EM854_RS05470 1103458..1103799 - 342 WP_000976492.1 YebY family protein -
EM854_RS05475 1103812..1104684 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
EM854_RS05480 1104688..1105062 - 375 WP_000204699.1 CopC domain-containing protein YobA -
EM854_RS05485 1105201..1105431 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EM854_RS05490 1105533..1106189 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EM854_RS05495 1106213..1106875 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T116412 NZ_CP034738:c1103300-1103197 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT116412 NZ_CP034738:1103159-1103430 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References