Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5570890..5571545 Replicon chromosome
Accession NZ_CP034725
Organism Pseudomonas brassicacearum strain 3Re2-7

Toxin (Protein)


Gene name higB Uniprot ID I4K1R5
Locus tag ELZ14_RS25720 Protein ID WP_003205392.1
Coordinates 5571201..5571545 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ELZ14_RS25715 Protein ID WP_003205391.1
Coordinates 5570890..5571204 (-) Length 105 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ14_RS25690 5566936..5567853 + 918 WP_003205387.1 LysR family transcriptional regulator -
ELZ14_RS25695 5568003..5569016 + 1014 WP_003205388.1 diguanylate cyclase -
ELZ14_RS25700 5569108..5569851 + 744 WP_003205389.1 DUF72 domain-containing protein -
ELZ14_RS25705 5569973..5570677 + 705 WP_003205390.1 hypothetical protein -
ELZ14_RS25715 5570890..5571204 - 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
ELZ14_RS25720 5571201..5571545 - 345 WP_003205392.1 toxin HigB-2 Toxin
ELZ14_RS25725 5571685..5572572 - 888 WP_003205393.1 heme o synthase -
ELZ14_RS25730 5572584..5572919 - 336 WP_003205394.1 cytochrome o ubiquinol oxidase subunit IV -
ELZ14_RS25735 5572920..5573546 - 627 WP_003205395.1 cytochrome o ubiquinol oxidase subunit III -
ELZ14_RS25740 5573550..5575580 - 2031 WP_003205396.1 cytochrome o ubiquinol oxidase subunit I -
ELZ14_RS25745 5575584..5576531 - 948 WP_003205397.1 ubiquinol oxidase subunit II -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(47-87)


Sequences


Toxin        


Download         Length: 115 a.a.        Molecular weight: 13735.68 Da        Isoelectric Point: 8.3860

>T116410 WP_003205392.1 NZ_CP034725:c5571545-5571201 [Pseudomonas brassicacearum]
MRTLFFETTTFTDTVGHYLTDDEYRLLQSYMLQHPEVGDVIPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T116410 NZ_CP034725:c5571545-5571201 [Pseudomonas brassicacearum]
ATGCGTACCCTATTTTTTGAAACGACTACATTCACCGACACGGTTGGCCATTACCTGACTGATGATGAGTATCGCCTGCT
TCAGTCCTATATGCTGCAGCATCCAGAGGTTGGTGACGTCATACCACGTACCGGCGGCTTTCGTAAGCTGCGCTGGTTCG
ATGAGCGTCGTGGTAAAGGGAAGCGAGGCGGGTTGCGCGTTATTTACTATTGGCTCATGAACGATCGTCAGTTCTGGATG
TTCGCGATTTATGACAAGGACGAGTTGGAAAACCTGACCTCCGAGCAAGAGAAGACGCTCAAACGCGCCATAGAAGCTGA
GTTGAAAGTACGAGGTACCTTATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT116410 WP_003205391.1 NZ_CP034725:c5571204-5570890 [Pseudomonas brassicacearum]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT116410 NZ_CP034725:c5571204-5570890 [Pseudomonas brassicacearum]
ATGAAAAAGCGCGATCTGTTTGCCGAGATGATGCAAGGCGTCGAGGAGATGGCCGCCCACCGGGAGGGCAAGATTACCCT
TCGCCAGATATCGATCGAAGACAAACCGGTTCCCGAGGTGTCTGCCCAAGAAATCGTGGCGTTGCGCGACAAGCTCCACA
TGTCTCAAGCCGTTTTCGCCAAGAGCATCAGGACCAGTCCAGGTACGCTCAGGAACTGGGAGCAGGAGAAGTCCAAGCCT
AACGCCCAGGCGGCTTTGTTGATCAAGCTGGTCGAGAAGTTTCCAGATATGGTCGAACGGCTTGGCGCTGTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB I4K1R5


Antitoxin

Source ID Structure

References