Detailed information of TA system TA116409

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 4520857..4521449
• Replicon: chromosome
• Accession: NZ_CP034725
• Organism: Pseudomonas brassicacearum strain 3Re2-7

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: ELZ14_RS20565
• Protein ID: WP_149632593.1
• Coordinates: 4520857..4521135 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: ELZ14_RS20570
• Protein ID: WP_149632438.1
• Coordinates: 4521144..4521449 (+)
• Length: 102 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ14_RS20550	4516072..4519641	-	3570	WP_149632436.1	phage tail protein	-
ELZ14_RS20555	4519699..4520295	-	597	WP_042956541.1	tail assembly protein	-
ELZ14_RS20565	4520857..4521135	+	279	WP_149632593.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ELZ14_RS20570	4521144..4521449	+	306	WP_149632438.1	HigA family addiction module antidote protein	Antitoxin
ELZ14_RS20575	4521446..4522213	-	768	WP_149632439.1	C40 family peptidase	-
ELZ14_RS20580	4522216..4522965	-	750	WP_149632440.1	phage minor tail protein L	-
ELZ14_RS20585	4522975..4523313	-	339	WP_039012512.1	phage tail protein	-
ELZ14_RS20590	4523313..4526360	-	3048	WP_149632441.1	phage tail tape measure protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4507325..4563605	56280

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (13-92)

Antitoxin

• Toxin-antitoxin system, antidote protein, HigA (4-97)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10451.81 Da
• Isoelectric Point: 7.8574

>T116409 WP_149632593.1 NZ_CP034725:4520857-4521135 [Pseudomonas brassicacearum]
MIISFRCGDTHTLFTTGASRKWAAILSVAQRKLTLLDQATALQDLRSPPGNRLEALQGNRQGQYSIRINDQYRICFTWDA
QGPENVEIVDYH

Nucleotide

• Length: 279 bp

>T116409 NZ_CP034725:4520857-4521135 [Pseudomonas brassicacearum]
ATGATCATCAGTTTCCGTTGTGGCGATACCCACACCCTGTTCACCACTGGCGCCTCTCGGAAATGGGCGGCAATTCTGTC
CGTGGCGCAACGAAAACTGACCTTGCTTGATCAGGCGACCGCATTGCAGGATTTGCGGTCACCGCCCGGCAATCGGCTGG
AAGCACTACAAGGGAACCGACAAGGTCAATACAGCATCCGAATTAATGATCAGTACCGTATTTGTTTTACCTGGGATGCT
CAGGGACCCGAAAACGTTGAAATTGTAGACTACCACTGA

Antitoxin

Protein

• Length: 102 a.a.
• Molecular weight: 11357.00 Da
• Isoelectric Point: 6.0724

>AT116409 WP_149632438.1 NZ_CP034725:4521144-4521449 [Pseudomonas brassicacearum]
VFNNGMRPVHPGEILREEFLHPLDLTPTALARMLHVSPPTVNEIVREKRGITADVALRLAACFDTSAQFWTNLQATYDLR
RAEIDHGADIIKQVERAPELA

Nucleotide

• Length: 306 bp

>AT116409 NZ_CP034725:4521144-4521449 [Pseudomonas brassicacearum]
GTGTTTAATAACGGCATGCGCCCTGTCCATCCGGGCGAAATTCTCAGGGAAGAATTTCTTCACCCGCTGGACCTAACGCC
GACCGCTCTCGCGAGGATGCTCCACGTGTCCCCGCCAACGGTAAATGAAATCGTCCGTGAAAAGCGAGGAATCACTGCAG
ACGTCGCGCTGCGCTTGGCTGCCTGCTTTGATACCAGCGCACAGTTCTGGACCAACCTCCAGGCCACGTATGACTTGCGT
CGTGCGGAGATTGATCATGGCGCAGATATCATTAAGCAAGTTGAGCGAGCCCCAGAACTGGCTTAG