Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2243514..2244055 Replicon chromosome
Accession NZ_CP034447
Organism Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EJ070_RS10845 Protein ID WP_126091358.1
Coordinates 2243768..2244055 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EJ070_RS10840 Protein ID WP_126091357.1
Coordinates 2243514..2243768 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ070_RS10810 2238620..2239246 - 627 WP_126091351.1 LysE family translocator -
EJ070_RS10815 2239373..2239669 + 297 WP_126091352.1 type II toxin-antitoxin system RelE/ParE family toxin -
EJ070_RS10820 2239677..2239985 + 309 WP_126091353.1 HigA family addiction module antidote protein -
EJ070_RS10825 2240105..2241946 + 1842 WP_126091354.1 DNA helicase RecQ -
EJ070_RS10830 2242028..2242480 - 453 WP_126091355.1 cupin domain-containing protein -
EJ070_RS10835 2242477..2243106 - 630 WP_126091356.1 TetR/AcrR family transcriptional regulator -
EJ070_RS10840 2243514..2243768 + 255 WP_126091357.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EJ070_RS10845 2243768..2244055 + 288 WP_126091358.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJ070_RS10850 2244117..2245733 - 1617 WP_126091359.1 caspase family protein -
EJ070_RS10855 2245979..2246518 + 540 WP_126091360.1 hypothetical protein -
EJ070_RS36240 2246547..2246711 + 165 WP_189350477.1 hypothetical protein -
EJ070_RS36245 2246978..2247325 - 348 WP_189350479.1 hypothetical protein -
EJ070_RS36250 2247312..2247704 + 393 WP_189350482.1 Spy/CpxP family protein refolding chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10838.46 Da        Isoelectric Point: 6.6442

>T116073 WP_126091358.1 NZ_CP034447:2243768-2244055 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
MGFRLSIAAEEDIIGIAEQGVRVSGPVQARQYHDELFAIFDLIVANPRIARERLELSPPMRIHPFKAHLVVYRIEGDGDI
LIVRVRHGHEDWARS

Download         Length: 288 bp

>T116073 NZ_CP034447:2243768-2244055 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
ATGGGTTTCCGCCTATCGATAGCGGCGGAAGAGGACATTATCGGCATTGCCGAGCAGGGTGTCCGCGTGTCTGGCCCCGT
GCAAGCCAGACAATATCATGACGAGTTGTTCGCGATCTTCGATCTGATCGTCGCCAATCCGCGCATCGCGCGGGAGCGAC
TTGAGTTATCACCGCCGATGCGAATCCATCCGTTCAAGGCCCATCTAGTCGTTTACCGGATCGAGGGAGACGGCGACATC
CTCATTGTCCGAGTGCGTCACGGGCACGAGGATTGGGCGAGAAGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9445.61 Da        Isoelectric Point: 8.5309

>AT116073 WP_126091357.1 NZ_CP034447:2243514-2243768 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
MATMNVSLPDPMKAWVEAQTETGRYANASDYVRDLIRKDQERNDKIAAMQSFVDDGLKSGIGRRSKDELFAEAVNRAEAP
RGKR

Download         Length: 255 bp

>AT116073 NZ_CP034447:2243514-2243768 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
ATGGCGACGATGAACGTATCCTTGCCCGATCCCATGAAGGCGTGGGTGGAGGCGCAGACTGAAACGGGGCGTTACGCCAA
TGCGAGCGATTACGTGCGTGATCTGATCCGCAAAGATCAGGAGCGCAACGACAAGATTGCGGCCATGCAGAGCTTTGTCG
ATGACGGCCTGAAGAGCGGTATCGGCAGGCGCTCCAAGGACGAGCTTTTCGCAGAGGCGGTCAACCGGGCAGAGGCGCCA
CGCGGCAAGCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References