Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 2316477..2316983 Replicon chromosome
Accession NZ_CP034438
Organism Flaviflexus salsibiostraticola strain KCTC 33148

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EJO69_RS10805 Protein ID WP_126041735.1
Coordinates 2316729..2316983 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EJO69_RS10800 Protein ID WP_126041733.1
Coordinates 2316477..2316728 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJO69_RS10785 2312404..2313668 + 1265 WP_126042319.1 IS3 family transposase -
EJO69_RS10790 2313789..2314466 + 678 WP_126041729.1 hypothetical protein -
EJO69_RS10795 2314463..2316334 + 1872 WP_164519950.1 chorismate-binding protein -
EJO69_RS10800 2316477..2316728 + 252 WP_126041733.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EJO69_RS10805 2316729..2316983 + 255 WP_126041735.1 Txe/YoeB family addiction module toxin Toxin
EJO69_RS10810 2317131..2317571 + 441 WP_126041736.1 YtoQ family protein -
EJO69_RS10815 2317771..2318130 + 360 WP_126041738.1 VOC family protein -
EJO69_RS10820 2318166..2319518 - 1353 WP_126041740.1 NAD(P)/FAD-dependent oxidoreductase -
EJO69_RS10825 2319821..2320591 + 771 WP_126041742.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
EJO69_RS10830 2320651..2320992 - 342 WP_126041743.1 cytoplasmic protein -
EJO69_RS10835 2321193..2321732 + 540 WP_126041745.1 DUF421 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10043.50 Da        Isoelectric Point: 8.8571

>T116031 WP_126041735.1 NZ_CP034438:2316729-2316983 [Flaviflexus salsibiostraticola]
VRLVWDRHGWADYVYWQSADRRILKRINTLIDACLRDPFEGIGKPEQLKYGAQGAWSRRITDEHRLVYIVIDGDLIILQA
RYHY

Download         Length: 255 bp

>T116031 NZ_CP034438:2316729-2316983 [Flaviflexus salsibiostraticola]
GTGCGCCTGGTCTGGGATCGGCATGGCTGGGCGGACTATGTTTATTGGCAGTCCGCCGACCGTCGGATTCTCAAGCGGAT
CAACACGCTGATCGACGCCTGCCTGCGAGATCCATTTGAGGGGATCGGCAAGCCGGAGCAGCTCAAGTACGGTGCGCAGG
GTGCGTGGTCGCGCCGCATCACCGACGAGCACCGTTTGGTGTATATCGTCATCGATGGCGATCTGATCATCCTCCAAGCG
CGGTATCACTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9538.63 Da        Isoelectric Point: 4.6995

>AT116031 WP_126041733.1 NZ_CP034438:2316477-2316728 [Flaviflexus salsibiostraticola]
MSMSASEARKTLFPLIERVNDNHEAVEIVSRKGNAVLMPADEYVSWQETAYLFRSPANARRLLDAYERARAGETEVHELD
REE

Download         Length: 252 bp

>AT116031 NZ_CP034438:2316477-2316728 [Flaviflexus salsibiostraticola]
ATGTCCATGAGTGCAAGCGAGGCGCGCAAGACGCTGTTCCCGCTGATCGAGCGTGTGAACGACAATCACGAGGCGGTCGA
GATCGTCTCTCGCAAGGGTAATGCCGTGCTCATGCCTGCGGATGAGTATGTGTCATGGCAGGAGACTGCCTATCTATTTC
GATCACCGGCCAATGCCCGCCGGCTGCTCGATGCCTACGAGCGTGCTCGAGCTGGCGAGACCGAGGTTCACGAGCTCGAT
CGGGAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References