Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 7616150..7616856 Replicon chromosome
Accession NZ_CP034432
Organism Bradyrhizobium sp. LCT2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EI171_RS36055 Protein ID WP_161536121.1
Coordinates 7616431..7616856 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EI171_RS36050 Protein ID WP_161536120.1
Coordinates 7616150..7616434 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI171_RS36030 7611222..7612196 - 975 WP_161536117.1 sugar ABC transporter permease -
EI171_RS36035 7612196..7613281 - 1086 WP_161536118.1 ABC transporter ATP-binding protein -
EI171_RS36040 7613294..7614370 - 1077 WP_028175056.1 ABC transporter ATP-binding protein -
EI171_RS36045 7614367..7615917 - 1551 WP_161536119.1 glycerol-3-phosphate dehydrogenase -
EI171_RS36050 7616150..7616434 + 285 WP_161536120.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EI171_RS36055 7616431..7616856 + 426 WP_161536121.1 type II toxin-antitoxin system VapC family toxin Toxin
EI171_RS36060 7616859..7617704 - 846 WP_060910813.1 DeoR/GlpR family DNA-binding transcription regulator -
EI171_RS36065 7617796..7618482 - 687 WP_161536122.1 HAD-IA family hydrolase -
EI171_RS36070 7618638..7619105 + 468 WP_011085218.1 nuclear transport factor 2 family protein -
EI171_RS36075 7619204..7619395 - 192 WP_028175062.1 hypothetical protein -
EI171_RS36080 7619586..7620017 - 432 WP_028175063.1 acyl-CoA thioesterase -
EI171_RS36085 7620097..7620906 - 810 WP_161536123.1 fatty acid desaturase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15455.60 Da        Isoelectric Point: 4.3475

>T116017 WP_161536121.1 NZ_CP034432:7616431-7616856 [Bradyrhizobium sp. LCT2]
VNLLLDTNILSEVQRPAPSPNVLAWLDTIDEDRAFISVASIAELRRGIALLEDGRRRSALAAWLADDLPTRFGERVLPID
QAVVERWGDLMAQSRRSGVALSVMDGFFAATALANDLTLATRNVKDFAAFGVPLLNPWDDP

Download         Length: 426 bp

>T116017 NZ_CP034432:7616431-7616856 [Bradyrhizobium sp. LCT2]
GTGAACCTGCTGCTCGACACCAACATACTGTCGGAAGTTCAGCGGCCAGCCCCCTCGCCGAATGTCTTGGCTTGGCTTGA
CACGATCGATGAAGATCGTGCGTTCATCAGCGTCGCATCGATCGCCGAGCTTCGCCGCGGCATCGCATTGCTGGAGGATG
GCCGCCGGCGCTCGGCACTGGCCGCTTGGCTTGCCGATGATCTGCCGACGCGGTTTGGCGAACGTGTCCTGCCGATCGAC
CAGGCGGTGGTCGAGCGCTGGGGCGACCTGATGGCTCAGAGCCGCCGCAGCGGCGTTGCTCTGTCCGTCATGGATGGCTT
CTTTGCCGCGACCGCGCTTGCAAACGATCTCACGCTCGCCACGCGCAATGTGAAGGATTTTGCTGCATTCGGCGTCCCCC
TGCTCAATCCGTGGGACGACCCATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10254.51 Da        Isoelectric Point: 6.2202

>AT116017 WP_161536120.1 NZ_CP034432:7616150-7616434 [Bradyrhizobium sp. LCT2]
MADHNTAPDTLPTDDTWTLANAKARLSEVIDRAQTGPQIITRHGKPNAVVVSAEEWARKTARKGTLAEFLLASPLRGADL
ALDRTHDAPRDEMP

Download         Length: 285 bp

>AT116017 NZ_CP034432:7616150-7616434 [Bradyrhizobium sp. LCT2]
ATGGCCGACCACAACACTGCACCCGACACGCTTCCGACTGATGACACGTGGACGCTTGCCAACGCCAAGGCACGACTGTC
CGAGGTGATCGACCGTGCCCAGACCGGCCCCCAGATCATCACCCGTCACGGCAAGCCGAACGCCGTGGTCGTTTCCGCCG
AGGAATGGGCCCGCAAGACCGCACGCAAAGGCACGCTGGCCGAATTCCTGCTGGCCTCTCCGCTGCGCGGCGCCGACCTC
GCACTTGATCGCACGCACGATGCGCCGCGCGACGAGATGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References