Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1244179..1244450 Replicon chromosome
Accession NZ_CP034404
Organism Escherichia coli strain CRE10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1244217..1244320 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1244179..1244450 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJC75_RS07955 1241336..1242775 + 1440 WP_024198516.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EJC75_RS07960 1242893..1243129 + 237 WP_001295499.1 DUF1480 family protein -
EJC75_RS07965 1243234..1243425 + 192 WP_000457842.1 YebW family protein -
EJC75_RS07970 1243426..1244082 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1244179..1244450 + 272 - - Antitoxin
- 1244217..1244320 - 104 - - Toxin
EJC75_RS07975 1244478..1244819 - 342 WP_000976492.1 YebY family protein -
EJC75_RS07980 1244832..1245704 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
EJC75_RS07985 1245708..1246082 - 375 WP_000204699.1 CopC domain-containing protein YobA -
EJC75_RS07990 1246221..1246451 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EJC75_RS07995 1246553..1247209 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EJC75_RS08000 1247233..1247895 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T115921 NZ_CP034404:c1244320-1244217 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT115921 NZ_CP034404:1244179-1244450 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References