Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 1357292..1357839 | Replicon | chromosome |
| Accession | NZ_CP034289 | ||
| Organism | Vibrio parahaemolyticus strain 20140722001-1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | EHC64_RS06715 | Protein ID | WP_140060746.1 |
| Coordinates | 1357537..1357839 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3A269 |
| Locus tag | EHC64_RS06710 | Protein ID | WP_005448240.1 |
| Coordinates | 1357292..1357549 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EHC64_RS06660 | 1352293..1352385 | + | 93 | WP_072886081.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06665 | 1352839..1352931 | + | 93 | WP_017821981.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06670 | 1352961..1353422 | + | 462 | WP_069218288.1 | hypothetical protein | - |
| EHC64_RS06675 | 1353437..1353529 | + | 93 | WP_074531776.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06680 | 1353967..1354056 | + | 90 | WP_075984317.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06685 | 1354086..1354319 | + | 234 | WP_005377029.1 | hypothetical protein | - |
| EHC64_RS06690 | 1354579..1355502 | + | 924 | WP_020838889.1 | zinc dependent phospholipase C family protein | - |
| EHC64_RS06695 | 1355499..1355897 | + | 399 | WP_023623455.1 | hypothetical protein | - |
| EHC64_RS06700 | 1356045..1356554 | + | 510 | WP_069523627.1 | AAA family ATPase | - |
| EHC64_RS06705 | 1356690..1357103 | + | 414 | WP_020838843.1 | hypothetical protein | - |
| EHC64_RS06710 | 1357292..1357549 | + | 258 | WP_005448240.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| EHC64_RS06715 | 1357537..1357839 | + | 303 | WP_140060746.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| EHC64_RS06720 | 1357875..1357967 | + | 93 | WP_077673135.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06730 | 1358914..1359084 | + | 171 | Protein_1177 | DUF3265 domain-containing protein | - |
| EHC64_RS27300 | 1359098..1359589 | + | 492 | WP_025553544.1 | hypothetical protein | - |
| EHC64_RS06735 | 1359621..1359713 | + | 93 | WP_193237466.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06740 | 1359743..1360270 | + | 528 | WP_159408084.1 | hypothetical protein | - |
| EHC64_RS06745 | 1360711..1360851 | + | 141 | WP_180761348.1 | DUF3265 domain-containing protein | - |
| EHC64_RS06750 | 1360883..1361401 | + | 519 | WP_193237467.1 | GNAT family N-acetyltransferase | - |
| EHC64_RS06755 | 1361542..1362006 | + | 465 | WP_159408085.1 | GNAT family N-acetyltransferase | - |
| EHC64_RS06765 | 1362602..1362733 | + | 132 | WP_158173963.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 1350338..1441359 | 91021 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11592.48 Da Isoelectric Point: 4.8951
>T115685 WP_140060746.1 NZ_CP034289:1357537-1357839 [Vibrio parahaemolyticus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIVSKVERLEAFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIVSKVERLEAFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T115685 NZ_CP034289:1357537-1357839 [Vibrio parahaemolyticus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGCTATCCGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAACAATTGGTTCAAACGATCGTTTCTAAAGTCGAGCGCTTAGAGGCTTTCCCTGAATCGGGTCGCATTCCGC
CTGAATTAGAACATCTAAGCTATCGTGAAGTTGTAGTTAATCCGTGCCGCGTTTTCTATAAACAAGACGGCGACAAAGTA
TTTATTCTGTTTGTTATGCGTGCTGAGAGAGACTTGCGTAAGTTCCTATTGAGCAAGCAATAA
ATGGCTGAAATAATCTGGACTGAGCCAGCGCTATCCGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAACAATTGGTTCAAACGATCGTTTCTAAAGTCGAGCGCTTAGAGGCTTTCCCTGAATCGGGTCGCATTCCGC
CTGAATTAGAACATCTAAGCTATCGTGAAGTTGTAGTTAATCCGTGCCGCGTTTTCTATAAACAAGACGGCGACAAAGTA
TTTATTCTGTTTGTTATGCGTGCTGAGAGAGACTTGCGTAAGTTCCTATTGAGCAAGCAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9606.10 Da Isoelectric Point: 6.7269
>AT115685 WP_005448240.1 NZ_CP034289:1357292-1357549 [Vibrio parahaemolyticus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT115685 NZ_CP034289:1357292-1357549 [Vibrio parahaemolyticus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACAAAAATCCTTGCCGATCTCCACGACACTAAAGAACCAGT
GTTAATTACCGAACATGGCAAGCCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAACGTGCATTAGCGGATGGTAAAGTGGTGAGTCACGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACAAAAATCCTTGCCGATCTCCACGACACTAAAGAACCAGT
GTTAATTACCGAACATGGCAAGCCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAACGTGCATTAGCGGATGGTAAAGTGGTGAGTCACGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|