Detailed information of TA system TA115551

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 35549..36174
• Replicon: plasmid pATCC14028
• Accession: NZ_CP034231
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium strain ATCC 14028

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: EIL76_RS24640
• Protein ID: WP_000911322.1
• Coordinates: 35549..35947 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: EIL76_RS24645
• Protein ID: WP_000450265.1
• Coordinates: 35947..36174 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EIL76_RS24625	31740..32234	+	495	WP_010999946.1	entry exclusion protein	-
EIL76_RS24630	32270..33001	+	732	WP_000782438.1	complement resistance protein TraT	-
EIL76_RS24635	33378..35540	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
EIL76_RS24640	35549..35947	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
EIL76_RS24645	35947..36174	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..95924	95924

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (5-92)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-84)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T115551 WP_000911322.1 NZ_CP034231:c35947-35549 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T115551 NZ_CP034231:c35947-35549 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT115551 WP_000450265.1 NZ_CP034231:c36174-35947 [Salmonella enterica subsp. enterica serovar Typhimurium]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT115551 NZ_CP034231:c36174-35947 [Salmonella enterica subsp. enterica serovar Typhimurium]
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