Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2462283..2462554 Replicon chromosome
Accession NZ_CP034106
Organism Escherichia coli strain RCAD0514

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2462413..2462516 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2462283..2462554 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGA47_RS11725 2458838..2459500 - 663 WP_000944256.1 exodeoxyribonuclease X -
EGA47_RS11730 2459524..2460180 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
EGA47_RS11735 2460282..2460512 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EGA47_RS11740 2460651..2461025 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EGA47_RS11745 2461029..2461901 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EGA47_RS11750 2461914..2462255 + 342 WP_000976472.1 YebY family protein -
- 2462283..2462554 - 272 - - Antitoxin
- 2462413..2462516 + 104 - - Toxin
EGA47_RS11755 2462651..2463307 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
EGA47_RS11760 2463308..2463499 - 192 WP_001338167.1 YebW family protein -
EGA47_RS11765 2463604..2463840 - 237 WP_001338166.1 DUF1480 family protein -
EGA47_RS11770 2463958..2465397 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T115253 NZ_CP034106:2462413-2462516 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT115253 NZ_CP034106:c2462554-2462283 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References