Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4348614..4349076 Replicon chromosome
Accession NZ_CP034078
Organism Pseudomonas syringae pv. pisi str. PP1

Toxin (Protein)


Gene name relE Uniprot ID A0A0P9XJI4
Locus tag N032_RS20030 Protein ID WP_003393317.1
Coordinates 4348795..4349076 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M2UJ05
Locus tag N032_RS20025 Protein ID WP_003393315.1
Coordinates 4348614..4348805 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N032_RS28310 4344914..4345324 + 411 WP_003346247.1 hypothetical protein -
N032_RS20010 4345328..4345706 - 379 Protein_3764 transposase -
N032_RS20015 4345969..4347081 - 1113 WP_024647935.1 hypothetical protein -
N032_RS20020 4347241..4348551 + 1311 WP_124733734.1 mechanosensitive ion channel family protein -
N032_RS20025 4348614..4348805 + 192 WP_003393315.1 hypothetical protein Antitoxin
N032_RS20030 4348795..4349076 + 282 WP_003393317.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N032_RS20035 4349354..4351474 + 2121 WP_024647853.1 hypothetical protein -
N032_RS20040 4351645..4352685 + 1041 WP_024647852.1 DUF4062 domain-containing protein -
N032_RS20045 4353038..4353544 - 507 WP_003402417.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4342289..4355578 13289


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10563.26 Da        Isoelectric Point: 9.7428

>T115154 WP_003393317.1 NZ_CP034078:4348795-4349076 [Pseudomonas syringae pv. pisi str. PP1]
MLVEWRPAARMNLKQILSYIADRNIRAASELGMAIEVATSALPQHPYLYRHGRVHGTREIVVHPNYLVVYKVTDRIEVLA
VLHARQAYPTDAG

Download         Length: 282 bp

>T115154 NZ_CP034078:4348795-4349076 [Pseudomonas syringae pv. pisi str. PP1]
ATGCTGGTTGAGTGGCGGCCGGCAGCACGAATGAACCTGAAGCAAATACTTTCCTACATCGCAGACAGAAATATACGAGC
AGCCAGCGAACTGGGAATGGCAATAGAAGTAGCCACTTCAGCCCTACCTCAACATCCTTACTTGTATCGCCATGGGCGAG
TGCATGGAACAAGGGAAATCGTTGTCCACCCTAATTATCTCGTTGTTTACAAAGTGACAGATCGGATCGAAGTTCTCGCT
GTACTTCACGCCAGGCAAGCCTACCCTACCGACGCTGGGTAG

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 6977.73 Da        Isoelectric Point: 4.2322

>AT115154 WP_003393315.1 NZ_CP034078:4348614-4348805 [Pseudomonas syringae pv. pisi str. PP1]
MSARISPIVSEFETEEQAASYDKWFRAQVQASINDPAPNISHDQVMAEMRALLESKQPPSDAG

Download         Length: 192 bp

>AT115154 NZ_CP034078:4348614-4348805 [Pseudomonas syringae pv. pisi str. PP1]
ATGAGCGCTCGAATTTCTCCAATCGTGTCGGAGTTTGAAACCGAGGAACAGGCCGCCAGCTACGACAAGTGGTTTCGTGC
GCAGGTCCAGGCGTCAATCAATGATCCGGCACCCAATATTTCACACGATCAGGTCATGGCCGAGATGCGTGCGCTTCTAG
AGTCTAAGCAGCCCCCGTCAGATGCTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9XJI4

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2UJ05

References