Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4490845..4491079 | Replicon | chromosome |
| Accession | NZ_CP034067 | ||
| Organism | Shigella sonnei strain FDAARGOS_524 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4490846..4490949 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4490845..4491079 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGX92_RS23385 | 4487279..4487539 | + | 261 | WP_077447296.1 | excisionase | - |
| EGX92_RS23390 | 4487568..4488022 | + | 455 | Protein_4385 | IS1-like element IS1A family transposase | - |
| EGX92_RS23395 | 4488117..4489345 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| EGX92_RS23400 | 4489356..4489601 | + | 246 | Protein_4387 | IS1 family transposase | - |
| EGX92_RS23405 | 4489638..4490714 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4490845..4491079 | + | 235 | - | - | Antitoxin |
| - | 4490846..4490949 | - | 104 | - | - | Toxin |
| EGX92_RS23410 | 4491107..4491448 | - | 342 | WP_000976476.1 | YebY family protein | - |
| EGX92_RS23415 | 4491461..4492333 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| EGX92_RS23420 | 4492337..4492711 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| EGX92_RS23425 | 4492850..4493080 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EGX92_RS23430 | 4493183..4493839 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| EGX92_RS23435 | 4493863..4494525 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 4471183..4496582 | 25399 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T115106 NZ_CP034067:c4490949-4490846 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT115106 NZ_CP034067:4490845-4491079 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
