Detailed information of TA system TA114740

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 229249..230696
• Replicon: chromosome
• Accession: NZ_CP033966
• Organism: Pigmentiphaga sp. H8

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: EGT29_RS01090
• Protein ID: WP_124687293.1
• Coordinates: 229249..230100 (-)
• Length: 284 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: EGT29_RS01095
• Protein ID: WP_124687294.1
• Coordinates: 230097..230696 (-)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGT29_RS01085	225457..229227	+	3771	WP_124687292.1	methionine synthase	-
EGT29_RS01090	229249..230100	-	852	WP_124687293.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EGT29_RS01095	230097..230696	-	600	WP_124687294.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
EGT29_RS01100	230766..231788	-	1023	WP_124687295.1	LacI family transcriptional regulator	-
EGT29_RS01105	231886..233091	+	1206	WP_124687296.1	CoA transferase	-
EGT29_RS01110	233088..233936	+	849	WP_161567647.1	CoA ester lyase	-
EGT29_RS01115	233956..234948	+	993	WP_124687298.1	tripartite tricarboxylate transporter substrate binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (37-267)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (8-53)

Sequences

Toxin

Protein

• Length: 284 a.a.
• Molecular weight: 31631.61 Da
• Isoelectric Point: 7.8711

>T114740 WP_124687293.1 NZ_CP033966:c230100-229249 [Pigmentiphaga sp. H8]
MTNARNTAASVRARLLNKARVNRQDFNLLLGRYALERILYRLSRSTYRGHFLLKGSLLFDLWFDMPHRPTHDADLLGFTQ
AEVPHLIKVFQEICAIACDDGVLFQPGTVRAAKIRKEANYAGIRVNLLGLLDGARCPVQIDIGFGDAVVPGPEEAQYPVI
LDEMPAPQLHVYPQYTVIAEKLEAIVSLGMGNTRMKDYFDLWVLVQHAEIDGAILTQAVHATFGRRGTPIPGGTPLGLAD
EFAQDRRKRQQWEAFLRKNELPQMPLDEIVGAIRPALLAAMHA

Nucleotide

• Length: 852 bp

>T114740 NZ_CP033966:c230100-229249 [Pigmentiphaga sp. H8]
ATGACGAATGCCCGCAATACCGCAGCCTCCGTACGAGCAAGGCTGCTCAACAAGGCTCGGGTCAACCGGCAGGACTTCAA
TTTGCTGCTCGGGCGCTACGCATTGGAACGCATCCTGTACCGCCTGAGCCGCTCGACGTATCGAGGCCACTTCCTGTTGA
AGGGATCCTTGCTGTTCGACCTGTGGTTCGACATGCCGCATCGTCCAACACACGACGCCGACCTGCTTGGCTTCACGCAG
GCGGAAGTGCCGCATCTGATCAAGGTATTTCAGGAGATCTGTGCCATTGCGTGCGATGACGGGGTGCTCTTCCAACCTGG
TACGGTCAGGGCAGCGAAAATTCGCAAAGAAGCCAACTACGCCGGCATCCGAGTGAACCTGCTGGGCTTGCTGGATGGAG
CACGATGCCCGGTGCAGATCGATATCGGTTTCGGCGATGCGGTGGTCCCCGGCCCCGAAGAGGCTCAATACCCTGTCATC
CTGGACGAAATGCCCGCGCCGCAGCTCCACGTCTATCCGCAATACACCGTCATCGCGGAAAAGTTGGAAGCCATCGTCTC
GCTCGGCATGGGCAACACACGCATGAAAGATTATTTCGATCTATGGGTGTTGGTTCAGCATGCGGAAATCGATGGGGCAA
TCCTGACCCAGGCTGTGCACGCGACATTTGGGCGGCGAGGTACGCCCATTCCCGGCGGCACACCCTTGGGATTGGCTGAC
GAGTTCGCACAGGACAGGCGAAAAAGGCAGCAATGGGAGGCATTCCTGCGCAAGAATGAATTGCCCCAGATGCCGCTGGA
CGAGATCGTTGGAGCCATACGCCCCGCCTTGCTGGCCGCGATGCACGCATAG

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 21959.70 Da
• Isoelectric Point: 10.4846

>AT114740 WP_124687294.1 NZ_CP033966:c230696-230097 [Pigmentiphaga sp. H8]
MDTAADKLLAIAREAGLIRARDLAPLGIARVALTRAVRQGQLQRLGRGLYGLPSRQISEHTTLAEVARRVPKGVICLLSA
LRFHGLTTQAPHEVWIAIGGKAAVPRLGYPPLRIVRFSATALSEGVEEHMVDGVLIRVTGVAKTVADCFKYRNKIGLDVA
LEALRESWRAKRMTSEELWHYASLCRVANVMRPYLESLE

Nucleotide

• Length: 600 bp

>AT114740 NZ_CP033966:c230696-230097 [Pigmentiphaga sp. H8]
ATGGATACCGCTGCCGACAAGCTACTGGCGATAGCCCGCGAGGCGGGGCTGATTCGCGCGCGAGATCTGGCGCCGCTGGG
CATTGCCCGCGTGGCCCTGACTCGCGCCGTGCGCCAGGGACAGCTGCAACGCCTGGGGCGAGGGCTGTATGGCCTGCCAT
CTCGCCAGATCTCCGAACACACGACACTGGCGGAAGTCGCCCGGCGAGTTCCCAAGGGAGTCATCTGCCTGCTGTCGGCA
CTGCGGTTCCACGGTCTGACGACTCAGGCCCCGCATGAGGTATGGATAGCCATCGGTGGCAAGGCCGCGGTGCCCAGGCT
TGGCTATCCGCCGCTGCGCATCGTGCGGTTTTCCGCCACGGCCCTGAGCGAAGGGGTGGAAGAGCATATGGTCGATGGTG
TCCTCATCCGTGTCACTGGGGTTGCCAAGACCGTGGCAGACTGCTTCAAGTACCGCAACAAGATTGGCCTGGACGTGGCC
CTGGAAGCGCTGCGTGAATCGTGGAGAGCAAAACGTATGACCAGTGAAGAGCTGTGGCACTACGCAAGCCTTTGCCGGGT
AGCCAACGTCATGCGCCCGTATCTGGAAAGCCTGGAATGA