Detailed information of TA system TA114558

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3701128..3701668
• Replicon: chromosome
• Accession: NZ_CP033875
• Organism: Caulobacter sp. FWC26

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CSW63_RS19165
• Protein ID: WP_082749629.1
• Coordinates: 3701387..3701668 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CSW63_RS19160
• Protein ID: WP_062097966.1
• Coordinates: 3701128..3701382 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSW63_RS23455	3696935..3697099	+	165	WP_168193690.1	hypothetical protein	-
CSW63_RS19145	3697096..3697563	-	468	WP_062093400.1	Lrp/AsnC ligand binding domain-containing protein	-
CSW63_RS19155	3698000..3701089	+	3090	WP_062097969.1	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	-
CSW63_RS19160	3701128..3701382	+	255	WP_062097966.1	hypothetical protein	Antitoxin
CSW63_RS19165	3701387..3701668	+	282	WP_082749629.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CSW63_RS19170	3701790..3703118	+	1329	WP_062097955.1	cellulase family glycosylhydrolase	-
CSW63_RS19175	3703203..3704819	+	1617	WP_062097953.1	carboxylesterase/lipase family protein	-
CSW63_RS23460	3704800..3704955	-	156	WP_156447789.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-92)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10860.56 Da
• Isoelectric Point: 6.4656

>T114558 WP_082749629.1 NZ_CP033875:3701387-3701668 [Caulobacter sp. FWC26]
MPRQLYLTAEAQRDIDRLYAWLLDKSPDAALRMIMLLEQHLTSLTDFPDRGRLVTLGIRELIVPFGGSRYVVRYEASPET
VFISRIWHGLEDR

Nucleotide

• Length: 282 bp

>T114558 NZ_CP033875:3701387-3701668 [Caulobacter sp. FWC26]
CTGCCCCGCCAGCTATATCTAACGGCGGAGGCGCAGCGCGACATTGATCGCCTCTACGCCTGGCTATTGGACAAAAGTCC
TGACGCGGCCCTGCGTATGATCATGCTGCTTGAGCAACACCTTACGAGCCTGACCGACTTCCCAGACCGAGGACGCTTGG
TCACGCTCGGCATTCGGGAGTTGATCGTTCCCTTCGGCGGCTCGCGTTACGTTGTCCGCTATGAAGCCAGCCCCGAGACC
GTCTTCATTTCGCGCATCTGGCACGGTCTAGAGGATCGCTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9386.57 Da
• Isoelectric Point: 6.0600

>AT114558 WP_062097966.1 NZ_CP033875:3701128-3701382 [Caulobacter sp. FWC26]
MADGFDIHIDPEQAARLKVLADQAHMSPQDYAMLLIDRGINQTASPSINPDPAIDRAIIDHAKRSGDFKPWSEVRDGLLA
RHQR

Nucleotide

• Length: 255 bp

>AT114558 NZ_CP033875:3701128-3701382 [Caulobacter sp. FWC26]
ATGGCCGATGGCTTCGACATTCATATTGATCCCGAGCAGGCGGCGCGGCTGAAGGTGCTGGCGGACCAAGCGCACATGTC
TCCGCAAGACTATGCGATGCTTTTGATTGATCGAGGGATCAATCAGACGGCCTCGCCTTCGATCAACCCGGACCCAGCCA
TCGATCGCGCCATCATCGATCACGCTAAGCGCTCGGGCGATTTCAAGCCGTGGTCTGAGGTGCGAGACGGCCTGCTAGCG
CGCCACCAACGTTAG