Detailed information of TA system TA113384

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2118867..2119423
• Replicon: chromosome
• Accession: NZ_CP033197
• Organism: Xanthomonas oryzae pv. oryzae strain KXO85

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EBA20_RS10680
• Protein ID: WP_027703932.1
• Coordinates: 2119133..2119423 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: EBA20_RS10675
• Protein ID: WP_011408759.1
• Coordinates: 2118867..2119145 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EBA20_RS10640	2114120..2114725	-	606	Protein_1917	DNA-3-methyladenine glycosylase	-
EBA20_RS10645	2114827..2115792	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
EBA20_RS10650	2115881..2116072	-	192	Protein_1919	transposase	-
EBA20_RS10660	2116237..2117421	+	1185	WP_011408397.1	IS256 family transposase	-
EBA20_RS10665	2118182..2118382	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
EBA20_RS25240	2118285..2118671	+	387	WP_205412094.1	hypothetical protein	-
EBA20_RS25245	2118583..2118786	+	204	WP_199285669.1	hypothetical protein	-
EBA20_RS10675	2118867..2119145	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
EBA20_RS10680	2119133..2119423	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EBA20_RS24935	2119684..2119881	+	198	WP_004541336.1	hypothetical protein	-
EBA20_RS10690	2120025..2120204	+	180	WP_015463309.1	hypothetical protein	-
EBA20_RS10710	2121068..2121469	-	402	WP_011259345.1	H-NS histone family protein	-
EBA20_RS10715	2121691..2121867	+	177	Protein_1929	DUF3606 domain-containing protein	-
EBA20_RS24940	2121883..2122089	+	207	Protein_1930	hypothetical protein	-
EBA20_RS10725	2122149..2122486	+	338	Protein_1931	ATP-dependent DNA ligase	-
EBA20_RS10730	2122562..2123653	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T113384 WP_027703932.1 NZ_CP033197:2119133-2119423 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T113384 NZ_CP033197:2119133-2119423 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT113384 WP_011408759.1 NZ_CP033197:2118867-2119145 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT113384 NZ_CP033197:2118867-2119145 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2