113238

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 310929..312276 Replicon chromosome
Accession NZ_CP033138
Organism Vibrio owensii strain 1700302

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag D0812_RS19210 Protein ID WP_122045120.1
Coordinates 311335..312276 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag D0812_RS19205 Protein ID WP_122045119.1
Coordinates 310929..311333 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0812_RS19185 308594..309046 - 453 WP_021018079.1 hypothetical protein -
D0812_RS19195 309626..309868 + 243 WP_122045118.1 hypothetical protein -
D0812_RS19200 310147..310740 + 594 WP_085343577.1 tyrosine-type recombinase/integrase -
D0812_RS19205 310929..311333 + 405 WP_122045119.1 S-adenosylhomocysteine hydrolase Antitoxin
D0812_RS19210 311335..312276 + 942 WP_122045120.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
D0812_RS19215 312296..313813 + 1518 WP_122045121.1 type I restriction-modification system subunit M -
D0812_RS30200 313803..315023 + 1221 WP_162998338.1 restriction endonuclease subunit S -
D0812_RS19225 315089..315925 + 837 WP_122045122.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 310147..326128 15981


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 35732.17 Da        Isoelectric Point: 5.4766

>T113238 WP_122045120.1 NZ_CP033138:311335-312276 [Vibrio owensii]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELAKVCPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAARKACINEIEQALTQSGRFNVETRSVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPQEVSAFDCVSIHATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCIAKLSMPELDSIDGLFKAVL
AEDIARFGNQHAEFVANPKQELQLGLKELEENAIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Download         Length: 942 bp

>T113238 NZ_CP033138:311335-312276 [Vibrio owensii]
ATGAACACACTAAAACAACAGTTCCTTGAGGTTTCCGATGCGCTTGAGCTCGGAAACCCAGCCATTATTGAAAAAGATTA
CTGGGTCGTGGCTTTACTGGCTGAGCTAGCGAAAGTTTGTCCTGAGCATCATCAAATGGTCTTTTCTGGCGGCACTGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCATTTGATGAA
CTGAGCCGAGCGAAAAAGAAAGCTGCGAGAAAGGCATGCATAAATGAGATTGAACAGGCGCTCACCCAGTCAGGGCGATT
TAACGTTGAAACGCGCTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACCCGCAGCAGTTTAGCCAAG
CCCCCTGTCTTCGCCCCATCATCAAGTTAGAGTTAATCGAAACTATTCCATTACTGGATGTGGAGTCGCGCAGTATTCAA
TCTCTGGTCGCAGAGTTGTACCAACAACCACAAGAAGTGAGTGCATTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATTATTTCAATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTAGTTCGCC
ACATCTACGATGTGCACTGCATAGCAAAACTCTCAATGCCAGAACTCGACTCGATTGACGGTCTATTCAAAGCGGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAACATGCCGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTTAA
AGAGCTTGAGGAAAATGCAATATTCCGCCAACGCTTTCAGGACTTCGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTGAAAAAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15153.57 Da        Isoelectric Point: 10.4983

>AT113238 WP_122045119.1 NZ_CP033138:310929-311333 [Vibrio owensii]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVLQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALMRE
ILKMKGVDFEMDSLSLQSLSGTSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT113238 NZ_CP033138:310929-311333 [Vibrio owensii]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCCCTGAGGCAGCTTGTGCTGCAAGGTGAGTTAATGAAGCTTGGCTATGGCTTGT
ATACCAAAGCAAGAATCAATAGCCTCACAGGTAAGCCTATGCCGACTAATCCGGGAGGGACCGATGCCCTTATGCGAGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGCACTAGCACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGACCCAAAACAGTTTAATCGCAAACTGGTGGTTGGTAGCCGTGTGCTGAACTTACCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References