Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 310929..312276 Replicon chromosome
Accession NZ_CP033138
Organism Vibrio owensii strain 1700302

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag D0812_RS19210 Protein ID WP_122045120.1
Coordinates 311335..312276 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag D0812_RS19205 Protein ID WP_122045119.1
Coordinates 310929..311333 (+) Length 135 a.a.

Genomic Context

D0812_RS19195D0812_RS19200D0812_RS19205D0812_RS19210D0812_RS19215D0812_RS30200D0812_RS19225D0812_RS19185
Location: 309626..309868 (243 bp)
Type: Others
Protein ID: WP_122045118.1
Location: 310147..310740 (594 bp)
Type: Others
Protein ID: WP_085343577.1
Location: 310929..311333 (405 bp)
Type: Antitoxin
Protein ID: WP_122045119.1
Location: 311335..312276 (942 bp)
Type: Toxin
Protein ID: WP_122045120.1
Location: 312296..313813 (1518 bp)
Type: Others
Protein ID: WP_122045121.1
Location: 313803..315023 (1221 bp)
Type: Others
Protein ID: WP_162998338.1
Location: 315089..315925 (837 bp)
Type: Others
Protein ID: WP_122045122.1
Location: 308594..309046 (453 bp)
Type: Others
Protein ID: WP_021018079.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0812_RS19185308594..309046-453WP_021018079.1hypothetical protein-
D0812_RS19195309626..309868+243WP_122045118.1hypothetical protein-
D0812_RS19200310147..310740+594WP_085343577.1tyrosine-type recombinase/integrase-
D0812_RS19205310929..311333+405WP_122045119.1S-adenosylhomocysteine hydrolaseAntitoxin
D0812_RS19210311335..312276+942WP_122045120.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
D0812_RS19215312296..313813+1518WP_122045121.1type I restriction-modification system subunit M-
D0812_RS30200313803..315023+1221WP_162998338.1restriction endonuclease subunit S-
D0812_RS19225315089..315925+837WP_122045122.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--310147..32612815981


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 35732.17 Da        Isoelectric Point: 5.4766

>T113238 WP_122045120.1 NZ_CP033138:311335-312276 [Vibrio owensii]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELAKVCPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAARKACINEIEQALTQSGRFNVETRSVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPQEVSAFDCVSIHATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCIAKLSMPELDSIDGLFKAVL
AEDIARFGNQHAEFVANPKQELQLGLKELEENAIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Download         Length: 942 bp

>T113238 NZ_CP033138:311335-312276 [Vibrio owensii]
ATGAACACACTAAAACAACAGTTCCTTGAGGTTTCCGATGCGCTTGAGCTCGGAAACCCAGCCATTATTGAAAAAGATTA
CTGGGTCGTGGCTTTACTGGCTGAGCTAGCGAAAGTTTGTCCTGAGCATCATCAAATGGTCTTTTCTGGCGGCACTGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCATTTGATGAA
CTGAGCCGAGCGAAAAAGAAAGCTGCGAGAAAGGCATGCATAAATGAGATTGAACAGGCGCTCACCCAGTCAGGGCGATT
TAACGTTGAAACGCGCTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACCCGCAGCAGTTTAGCCAAG
CCCCCTGTCTTCGCCCCATCATCAAGTTAGAGTTAATCGAAACTATTCCATTACTGGATGTGGAGTCGCGCAGTATTCAA
TCTCTGGTCGCAGAGTTGTACCAACAACCACAAGAAGTGAGTGCATTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATTATTTCAATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTAGTTCGCC
ACATCTACGATGTGCACTGCATAGCAAAACTCTCAATGCCAGAACTCGACTCGATTGACGGTCTATTCAAAGCGGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAACATGCCGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTTAA
AGAGCTTGAGGAAAATGCAATATTCCGCCAACGCTTTCAGGACTTCGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTGAAAAAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15153.57 Da        Isoelectric Point: 10.4983

>AT113238 WP_122045119.1 NZ_CP033138:310929-311333 [Vibrio owensii]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVLQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALMRE
ILKMKGVDFEMDSLSLQSLSGTSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT113238 NZ_CP033138:310929-311333 [Vibrio owensii]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCCCTGAGGCAGCTTGTGCTGCAAGGTGAGTTAATGAAGCTTGGCTATGGCTTGT
ATACCAAAGCAAGAATCAATAGCCTCACAGGTAAGCCTATGCCGACTAATCCGGGAGGGACCGATGCCCTTATGCGAGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGCACTAGCACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGACCCAAAACAGTTTAATCGCAAACTGGTGGTTGGTAGCCGTGTGCTGAACTTACCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References