Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1969775..1969978 Replicon chromosome
Accession NZ_CP033102
Organism Enterobacter hormaechei strain L51

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1969868..1969971 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1969775..1969978 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8768_RS09325 1966325..1966987 - 663 WP_022648468.1 exodeoxyribonuclease X -
D8768_RS09330 1967012..1967650 - 639 WP_045623249.1 carbon-nitrogen hydrolase family protein -
D8768_RS09335 1967762..1967992 - 231 WP_003859784.1 DNA polymerase III subunit theta -
D8768_RS09340 1968130..1968501 + 372 WP_157508616.1 CopC domain-containing protein YobA -
D8768_RS09345 1968503..1969372 + 870 WP_045623248.1 copper homeostasis membrane protein CopD -
D8768_RS09350 1969389..1969727 + 339 WP_022648464.1 YebY family protein -
- 1969775..1969978 - 204 - - Antitoxin
- 1969868..1969971 + 104 - - Toxin
D8768_RS09355 1970049..1971134 - 1086 WP_157507326.1 phage integrase Arm DNA-binding domain-containing protein -
D8768_RS09360 1971103..1971375 - 273 WP_023300430.1 hypothetical protein -
D8768_RS09365 1971534..1971749 - 216 WP_157507328.1 DUF550 domain-containing protein -
D8768_RS09370 1971759..1971998 - 240 WP_032103556.1 DUF4222 domain-containing protein -
D8768_RS09375 1971976..1972314 - 339 WP_044158833.1 DUF2591 family protein -
D8768_RS09380 1972314..1972532 - 219 WP_157507330.1 TraR/DksA family transcriptional regulator -
D8768_RS09385 1972624..1972854 - 231 WP_006176201.1 hypothetical protein -
D8768_RS09390 1972851..1973069 - 219 WP_045617910.1 hypothetical protein -
D8768_RS09395 1973066..1974226 - 1161 WP_157507332.1 DNA cytosine methyltransferase -
D8768_RS09400 1974223..1974882 - 660 WP_157507334.1 DNA methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrB / gtrA 1964270..2035422 71152


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T113144 NZ_CP033102:1969868-1969971 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT113144 NZ_CP033102:c1969978-1969775 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References