Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2315296..2315530 Replicon chromosome
Accession NZ_CP032795
Organism Escherichia coli strain ERL06-2503

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2315426..2315529 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2315296..2315530 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z73_RS11875 2311851..2312513 - 663 WP_000944244.1 exodeoxyribonuclease X -
D8Z73_RS11880 2312537..2313193 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z73_RS11885 2313295..2313525 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z73_RS11890 2313664..2314038 + 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z73_RS11895 2314042..2314914 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z73_RS11900 2314927..2315268 + 342 WP_000976483.1 YebY family protein -
- 2315296..2315530 - 235 - - Antitoxin
- 2315426..2315529 + 104 - - Toxin
D8Z73_RS11905 2315661..2316737 - 1077 WP_045893699.1 phage integrase Arm DNA-binding domain-containing protein -
D8Z73_RS11910 2316703..2316984 - 282 WP_001311878.1 excisionase -
D8Z73_RS11915 2317091..2317279 - 189 WP_001356607.1 DUF1187 family protein -
- 2317095..2317273 + 179 NuclAT_0 - -
- 2317095..2317273 + 179 NuclAT_0 - -
- 2317095..2317273 + 179 NuclAT_0 - -
- 2317095..2317273 + 179 NuclAT_0 - -
D8Z73_RS11920 2317272..2317466 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
D8Z73_RS11925 2317523..2318332 - 810 WP_000166313.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2295216..2387046 91830


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112334 NZ_CP032795:2315426-2315529 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT112334 NZ_CP032795:c2315530-2315296 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References