Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2439492..2439763 Replicon chromosome
Accession NZ_CP032791
Organism Escherichia coli strain NZRM4165

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2439530..2439633 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2439492..2439763 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8Z75_RS12070 2436649..2438088 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
D8Z75_RS12075 2438206..2438442 + 237 WP_001295499.1 DUF1480 family protein -
D8Z75_RS12080 2438547..2438738 + 192 WP_001296140.1 YebW family protein -
D8Z75_RS12085 2438739..2439395 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2439492..2439763 + 272 - - Antitoxin
- 2439530..2439633 - 104 - - Toxin
D8Z75_RS12090 2439791..2440132 - 342 WP_000976483.1 YebY family protein -
D8Z75_RS12095 2440145..2441017 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
D8Z75_RS12100 2441021..2441395 - 375 WP_000168751.1 CopC domain-containing protein YobA -
D8Z75_RS12105 2441534..2441764 + 231 WP_000916763.1 DNA polymerase III subunit theta -
D8Z75_RS12110 2441866..2442522 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
D8Z75_RS12115 2442546..2443208 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112263 NZ_CP032791:c2439633-2439530 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112263 NZ_CP032791:2439492-2439763 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References