Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 39344..40023 Replicon plasmid p1
Accession NZ_CP032406
Organism Rhizobium rosettiformans strain MAE2-X

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D4A92_RS21760 Protein ID WP_203020549.1
Coordinates 39344..39775 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D4A92_RS21765 Protein ID WP_203020551.1
Coordinates 39772..40023 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4A92_RS21740 35284..36102 - 819 WP_203020543.1 ABC transporter permease -
D4A92_RS21745 36099..37043 - 945 WP_203020545.1 ABC transporter permease -
D4A92_RS21750 37221..38126 - 906 WP_203020547.1 LysR family transcriptional regulator -
D4A92_RS21755 38651..39303 + 653 Protein_32 Fic family protein -
D4A92_RS21760 39344..39775 - 432 WP_203020549.1 type II toxin-antitoxin system VapC family toxin Toxin
D4A92_RS21765 39772..40023 - 252 WP_203020551.1 plasmid stabilization protein Antitoxin
D4A92_RS21770 40711..41172 + 462 WP_203020554.1 mobile mystery protein A -
D4A92_RS21775 41169..41764 + 596 Protein_36 mobile mystery protein B -
D4A92_RS21780 42105..42782 - 678 WP_203020556.1 class I SAM-dependent methyltransferase -
D4A92_RS21785 42892..43356 + 465 WP_203020558.1 Rrf2 family transcriptional regulator -
D4A92_RS21790 43435..44166 - 732 WP_203020560.1 SDR family oxidoreductase -
D4A92_RS21795 44216..44764 - 549 WP_203020562.1 flavin reductase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG 1..510647 510647


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15544.07 Da        Isoelectric Point: 7.0158

>T111756 WP_203020549.1 NZ_CP032406:c39775-39344 [Rhizobium rosettiformans]
MILIDTNVISEPWKPAPAATVVAWLDAQAIETLFISAISVAELRFGIASMPIGRRQTILRNRLEDEVLPHFVERILPFTL
STSRLYSDLMAGARVSGKAIGKADGLIAATAAERGLVVATRDTSPFKAAGLKIINPWIDQNFD

Download         Length: 432 bp

>T111756 NZ_CP032406:c39775-39344 [Rhizobium rosettiformans]
ATGATCTTGATAGACACCAACGTGATATCGGAGCCGTGGAAGCCTGCTCCAGCTGCAACGGTTGTGGCTTGGTTGGATGC
CCAGGCAATCGAAACGCTCTTTATCTCTGCGATATCGGTTGCGGAGCTTCGGTTTGGCATCGCATCAATGCCTATCGGGC
GCCGTCAAACAATCCTCCGCAACCGTCTTGAGGATGAGGTCCTACCACATTTTGTTGAGCGTATTTTGCCCTTCACCCTA
AGCACCTCGCGGCTCTACTCTGATCTGATGGCAGGCGCGCGAGTATCCGGTAAAGCGATCGGCAAAGCCGATGGATTGAT
TGCGGCCACAGCTGCAGAGAGGGGGCTCGTTGTGGCAACGAGAGACACAAGCCCGTTCAAGGCAGCTGGATTGAAAATTA
TCAATCCGTGGATTGATCAGAACTTCGACTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9246.32 Da        Isoelectric Point: 4.8616

>AT111756 WP_203020551.1 NZ_CP032406:c40023-39772 [Rhizobium rosettiformans]
MPAVTIRNLSDETHRALRVRAAHHGRSTEAEIRDILEAAVRPSQRIKLGSLLVDIGREADLSDSDVEALQERDNTPAEPM
TFE

Download         Length: 252 bp

>AT111756 NZ_CP032406:c40023-39772 [Rhizobium rosettiformans]
ATGCCGGCAGTTACCATTCGGAATCTTTCTGATGAAACCCACCGCGCTTTGCGTGTGAGAGCAGCTCATCATGGCCGGAG
CACTGAGGCGGAAATTCGCGATATTCTTGAGGCCGCTGTTCGCCCGTCTCAACGCATAAAGCTCGGGTCATTGCTTGTGG
ACATTGGTCGGGAGGCCGACCTGTCAGACAGTGATGTTGAAGCTCTGCAAGAGCGCGACAATACGCCAGCTGAACCGATG
ACTTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References