Detailed information of TA system TA111597

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 840117..840816
• Replicon: chromosome
• Accession: NZ_CP032296
• Organism: Rahnella aquatilis strain ZF7

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A0H3F674
• Locus tag: D3Z09_RS03980
• Protein ID: WP_013574109.1
• Coordinates: 840364..840816 (+)
• Length: 151 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: D3Z09_RS03975
• Protein ID: WP_037035260.1
• Coordinates: 840117..840383 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D3Z09_RS03945	835124..835459	+	336	WP_013574102.1	DUF2002 family protein	-
D3Z09_RS03950	835524..836411	-	888	WP_013574103.1	AraC family transcriptional regulator	-
D3Z09_RS03955	836538..836978	-	441	WP_013574104.1	DUF1198 domain-containing protein	-
D3Z09_RS03960	837138..838082	-	945	WP_013574105.1	6-phosphofructokinase II	-
D3Z09_RS03965	838267..838797	+	531	WP_013574106.1	class IV adenylate cyclase	-
D3Z09_RS03970	838846..839838	-	993	WP_013574107.1	tRNA-modifying protein YgfZ	-
D3Z09_RS03975	840117..840383	+	267	WP_037035260.1	FAD assembly factor SdhE	Antitoxin
D3Z09_RS03980	840364..840816	+	453	WP_013574109.1	protein YgfX	Toxin
D3Z09_RS03985	840862..841380	-	519	WP_013574110.1	flavodoxin FldB	-
D3Z09_RS03990	841480..842439	+	960	WP_013574111.1	site-specific tyrosine recombinase XerD	-
D3Z09_RS03995	842465..843184	+	720	WP_013574112.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
D3Z09_RS04000	843191..844924	+	1734	WP_013574113.1	single-stranded-DNA-specific exonuclease RecJ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	luxS	741821..846153	104332

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-140)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 151 a.a.
• Molecular weight: 17573.93 Da
• Isoelectric Point: 11.8346

>T111597 WP_013574109.1 NZ_CP032296:840364-840816 [Rahnella aquatilis]
VALWRCDLRVSWRSQLISLGCYGAVMLLILLAPWPAGYWPVWMTLLLLVLFECIRSQRRITARTGEMILLEDNRLLWRGH
EWQIKQPVWMISHGVLLSLRREKRKGGLAQAMRSSRQRLWLASDSMSLEEWRRLRQILLSGTPRSPVKPG

Nucleotide

• Length: 453 bp

>T111597 NZ_CP032296:840364-840816 [Rahnella aquatilis]
GTGGCCCTGTGGCGATGTGATCTCAGGGTGTCCTGGCGCAGTCAGCTTATTTCACTGGGATGTTACGGTGCAGTGATGTT
GCTGATTTTGCTGGCACCCTGGCCTGCGGGTTACTGGCCGGTATGGATGACGTTGCTTTTGCTGGTGTTGTTTGAATGCA
TCCGCAGCCAGCGGCGTATTACAGCACGCACAGGTGAAATGATCCTGCTCGAGGATAACCGTCTTTTATGGCGCGGCCAT
GAATGGCAGATTAAACAGCCGGTATGGATGATAAGCCACGGCGTACTGCTCTCGCTTCGTCGCGAAAAACGTAAAGGCGG
GCTGGCGCAGGCGATGCGCAGTTCAAGGCAGCGGTTATGGCTGGCGTCGGACAGCATGAGTCTGGAAGAGTGGCGGCGGT
TGCGACAGATATTGCTCAGTGGCACTCCGCGTAGCCCGGTAAAACCGGGCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10464.97 Da
• Isoelectric Point: 5.1236

>AT111597 WP_037035260.1 NZ_CP032296:840117-840383 [Rahnella aquatilis]
MDINNRSRVHWACRRGMRELDISIMPFFEYEYDSLSETDKEVFVRLLTCDDPDLFNWLMNHGEPKDTELQRMVALIQTRN
KARGPVAM

Nucleotide

• Length: 267 bp

>AT111597 NZ_CP032296:840117-840383 [Rahnella aquatilis]
CTGGATATTAATAATCGTTCCCGCGTTCACTGGGCCTGCCGTCGTGGCATGCGCGAGCTGGATATCTCCATCATGCCGTT
CTTCGAATATGAATATGATTCGCTGAGCGAGACCGATAAAGAAGTATTTGTCCGCTTGCTGACCTGTGATGATCCGGATC
TGTTCAACTGGCTGATGAATCACGGCGAACCGAAAGACACCGAATTGCAGCGTATGGTCGCCCTTATTCAGACTCGAAAC
AAAGCCCGTGGCCCTGTGGCGATGTGA

Structures

Toxin

• AlphaFold DB: A0A0H3F674