Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5196667..5196812 Replicon chromosome
Accession NZ_CP032178
Organism Klebsiella pneumoniae strain AR_0135

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5196674..5196776 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5196667..5196812 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM382_RS26710 5192199..5193632 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM382_RS26715 5193748..5193987 + 240 WP_002911393.1 YebV family protein -
AM382_RS26720 5194085..5194276 + 192 WP_002911395.1 YebW family protein -
AM382_RS26725 5194273..5194926 - 654 WP_032418800.1 protein-serine/threonine phosphatase -
AM382_RS26730 5195083..5196051 + 969 WP_004151446.1 VirK/YbjX family protein -
AM382_RS29055 5196156..5196299 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5196667..5196812 + 146 - - Antitoxin
- 5196674..5196776 - 103 - - Toxin
AM382_RS26740 5196935..5197273 - 339 WP_002911404.1 YebY family protein -
AM382_RS26745 5197290..5198159 - 870 WP_023282759.1 copper homeostasis membrane protein CopD -
AM382_RS26750 5198163..5198537 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM382_RS26755 5198650..5198880 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM382_RS26760 5198959..5199618 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM382_RS26765 5199622..5201682 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111262 NZ_CP032178:c5196776-5196674 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111262 NZ_CP032178:5196667-5196812 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References