Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1930325..1930547 Replicon chromosome
Accession NZ_CP032066
Organism Escherichia coli strain E166

Toxin (Protein)


Gene name ldrD Uniprot ID A0A829L523
Locus tag D2J89_RS09225 Protein ID WP_000170738.1
Coordinates 1930440..1930547 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1930325..1930391 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D2J89_RS09205 1925766..1926668 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
D2J89_RS09210 1926679..1927662 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
D2J89_RS09215 1927659..1928663 + 1005 WP_000107036.1 dipeptide ABC transporter ATP-binding subunit DppF -
D2J89_RS09220 1928693..1929964 - 1272 WP_001318103.1 aromatic amino acid transport family protein -
- 1930325..1930391 - 67 - - Antitoxin
D2J89_RS09225 1930440..1930547 + 108 WP_000170738.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
D2J89_RS09230 1930923..1931030 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
D2J89_RS09235 1931117..1932796 - 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
D2J89_RS09240 1932793..1932984 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
D2J89_RS09245 1932981..1934552 - 1572 WP_001204944.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
D2J89_RS09250 1934825..1935013 + 189 WP_001063315.1 cellulose biosynthesis protein BcsR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3864.67 Da        Isoelectric Point: 9.0157

>T110958 WP_000170738.1 NZ_CP032066:1930440-1930547 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK

Download         Length: 108 bp

>T110958 NZ_CP032066:1930440-1930547 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATAGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT110958 NZ_CP032066:c1930391-1930325 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829L523

Antitoxin

Download structure file

References