Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 949265..949410 Replicon chromosome
Accession NZ_CP031934
Organism Klebsiella pneumoniae strain GZ-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 949272..949374 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 949265..949410 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1368_RS04780 944797..946230 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
D1368_RS04785 946346..946585 + 240 WP_002911393.1 YebV family protein -
D1368_RS04790 946683..946874 + 192 WP_002911395.1 YebW family protein -
D1368_RS04795 946871..947524 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
D1368_RS04800 947681..948649 + 969 WP_004151446.1 VirK/YbjX family protein -
D1368_RS04805 948754..948897 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 949265..949410 + 146 - - Antitoxin
- 949272..949374 - 103 - - Toxin
D1368_RS04810 949533..949871 - 339 WP_002911404.1 YebY family protein -
D1368_RS04815 949888..950757 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
D1368_RS04820 950761..951135 - 375 WP_004151448.1 CopC domain-containing protein YobA -
D1368_RS04825 951248..951478 + 231 WP_002911406.1 DNA polymerase III subunit theta -
D1368_RS04830 951557..952216 + 660 WP_002911407.1 exodeoxyribonuclease X -
D1368_RS04835 952220..954280 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T110816 NZ_CP031934:c949374-949272 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT110816 NZ_CP031934:949265-949410 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References