Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2062358..2062629 Replicon chromosome
Accession NZ_CP031898
Organism Escherichia coli O113:H21 strain FWSEC0010

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2062488..2062591 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2062358..2062629 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C8201_RS10070 2058914..2059576 - 663 WP_000944256.1 exodeoxyribonuclease X -
C8201_RS10075 2059600..2060255 - 656 Protein_1926 carbon-nitrogen hydrolase family protein -
C8201_RS10080 2060357..2060587 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C8201_RS10085 2060726..2061100 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C8201_RS10090 2061104..2061976 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C8201_RS10095 2061989..2062330 + 342 WP_000976492.1 YebY family protein -
- 2062358..2062629 - 272 - - Antitoxin
- 2062488..2062591 + 104 - - Toxin
C8201_RS10100 2062726..2063382 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C8201_RS10105 2063383..2063574 - 192 WP_001296140.1 YebW family protein -
C8201_RS10110 2063679..2063915 - 237 WP_001295499.1 DUF1480 family protein -
C8201_RS10115 2064033..2065472 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110533 NZ_CP031898:2062488-2062591 [Escherichia coli O113:H21]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT110533 NZ_CP031898:c2062629-2062358 [Escherichia coli O113:H21]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References