Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 678400..678993 Replicon chromosome
Accession NZ_CP031450
Organism Pseudomonas fluorescens strain SIK_W1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DXV65_RS03030 Protein ID WP_120447526.1
Coordinates 678691..678993 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DXV65_RS03025 Protein ID WP_120447525.1
Coordinates 678400..678687 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXV65_RS03005 674812..676872 - 2061 WP_065900248.1 TonB-dependent copper receptor -
DXV65_RS03010 676966..677325 - 360 WP_120447523.1 DUF2946 domain-containing protein -
DXV65_RS03015 677379..677861 - 483 WP_120447524.1 copper chaperone PCu(A)C -
DXV65_RS03020 677909..678304 - 396 WP_065900253.1 DUF2946 domain-containing protein -
DXV65_RS03025 678400..678687 - 288 WP_120447525.1 putative addiction module antidote protein Antitoxin
DXV65_RS03030 678691..678993 - 303 WP_120447526.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DXV65_RS03040 679513..679764 + 252 WP_065900255.1 hypothetical protein -
DXV65_RS03045 679924..681059 + 1136 Protein_574 IS3 family transposase -
DXV65_RS03050 681267..681755 - 489 WP_120447527.1 hypothetical protein -
DXV65_RS03055 681752..682030 - 279 WP_120447528.1 hypothetical protein -
DXV65_RS03060 682161..682883 - 723 WP_120447529.1 cobalt-precorrin-6A reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11659.38 Da        Isoelectric Point: 9.9393

>T109206 WP_120447526.1 NZ_CP031450:c678993-678691 [Pseudomonas fluorescens]
MIQFKKSKYFLEWLDSLRSKPARARVLARLDNAQWGNFGDCEALGNGVLEMRIHYGPGYRVYFTRRGEVVYLLLIGGDKS
TQKRDIQRAKQIAEDFEKTE

Download         Length: 303 bp

>T109206 NZ_CP031450:c678993-678691 [Pseudomonas fluorescens]
ATGATTCAATTTAAGAAGTCAAAATATTTTCTAGAATGGCTTGATTCGTTACGCAGTAAACCCGCGCGAGCACGCGTACT
GGCAAGGTTGGACAACGCGCAATGGGGCAACTTTGGAGACTGCGAAGCACTCGGAAATGGTGTTTTGGAAATGCGCATCC
ACTATGGCCCTGGCTATAGGGTCTATTTCACTCGCAGAGGCGAGGTGGTCTACCTGCTGTTGATCGGCGGCGACAAATCA
ACTCAGAAACGTGACATTCAGCGCGCAAAACAAATTGCAGAAGACTTTGAAAAAACGGAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10294.71 Da        Isoelectric Point: 4.4791

>AT109206 WP_120447525.1 NZ_CP031450:c678687-678400 [Pseudomonas fluorescens]
MSEFTDFDVAEHLKTPEDMAEYLEACFEEDAGDGLLIRSALNNIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATIM
KVMKALGLKLHATAV

Download         Length: 288 bp

>AT109206 NZ_CP031450:c678687-678400 [Pseudomonas fluorescens]
ATGAGTGAATTCACTGACTTCGACGTGGCAGAGCACCTAAAAACCCCAGAGGATATGGCCGAATATCTTGAAGCGTGCTT
CGAAGAAGATGCGGGCGACGGGCTTCTGATCCGTTCAGCCCTCAACAACATCGCCCGCGCCCAAGGCATGACCCAAGTAG
CCCGCGACGCCGGACTCGGAAGAGAAAGTTTGTACAAAGCCCTTTCCAGCACTGGCAATCCCGAGTTCGCGACTATCATG
AAAGTCATGAAAGCGTTGGGCCTCAAGCTTCACGCTACGGCGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References