Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2427814..2428082 Replicon chromosome
Accession NZ_CP031345
Organism Escherichia coli O145 strain RM12367-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2427852..2427955 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2427814..2428082 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE53_RS12670 2424971..2426410 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DXE53_RS12675 2426528..2426764 + 237 WP_001295499.1 DUF1480 family protein -
DXE53_RS12680 2426869..2427060 + 192 WP_001313035.1 YebW family protein -
DXE53_RS12685 2427061..2427717 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2427814..2428082 + 269 - - Antitoxin
- 2427852..2427955 - 104 - - Toxin
DXE53_RS12690 2428112..2428453 - 342 WP_000976475.1 YebY family protein -
DXE53_RS12695 2428466..2429338 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
DXE53_RS12700 2429342..2429716 - 375 WP_000168738.1 CopC domain-containing protein YobA -
DXE53_RS12705 2429855..2430085 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DXE53_RS12710 2430187..2430843 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
DXE53_RS12715 2430867..2431529 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleC / stx2B / stx2A 2419584..2501777 82193


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T109001 NZ_CP031345:c2427955-2427852 [Escherichia coli O145]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT109001 NZ_CP031345:2427814-2428082 [Escherichia coli O145]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References