Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 877973..878630 Replicon chromosome
Accession NZ_CP030874
Organism Raoultella sp. X13

Toxin (Protein)


Gene name cptA Uniprot ID A0A808XTM6
Locus tag DSD31_RS04345 Protein ID WP_004867355.1
Coordinates 878220..878630 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag DSD31_RS04340 Protein ID WP_004867358.1
Coordinates 877973..878239 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSD31_RS04315 873108..874541 - 1434 WP_004867372.1 6-phospho-beta-glucosidase -
DSD31_RS04320 874661..875389 - 729 WP_004867368.1 MurR/RpiR family transcriptional regulator -
DSD31_RS04325 875439..875750 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
DSD31_RS04330 875912..876571 + 660 WP_004867362.1 hemolysin III family protein -
DSD31_RS04335 876693..877676 - 984 WP_004867359.1 tRNA-modifying protein YgfZ -
DSD31_RS04340 877973..878239 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
DSD31_RS04345 878220..878630 + 411 WP_004867355.1 protein YgfX Toxin
DSD31_RS04350 878638..879159 - 522 WP_004867353.1 flavodoxin FldB -
DSD31_RS04355 879337..880233 + 897 WP_015585784.1 site-specific tyrosine recombinase XerD -
DSD31_RS04360 880256..880969 + 714 WP_004867349.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DSD31_RS04365 880975..882708 + 1734 WP_015585785.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16226.16 Da        Isoelectric Point: 11.3349

>T108121 WP_004867355.1 NZ_CP030874:878220-878630 [Raoultella sp. X13]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWIAADSMDAKEWRDLRRLVLQKPAQE

Download         Length: 411 bp

>T108121 NZ_CP030874:878220-878630 [Raoultella sp. X13]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCCTGGCGCTCACAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTGCTGCTGATGCCCTGGCCGCTGAGCTACACGCCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGTCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGATCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTGTTACAAAAACCGG
CACAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT108121 WP_004867358.1 NZ_CP030874:877973-878239 [Raoultella sp. X13]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT108121 NZ_CP030874:877973-878239 [Raoultella sp. X13]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGATC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCGCAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808XTM6

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References