Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 877973..878630 | Replicon | chromosome |
Accession | NZ_CP030874 | ||
Organism | Raoultella sp. X13 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A808XTM6 |
Locus tag | DSD31_RS04345 | Protein ID | WP_004867355.1 |
Coordinates | 878220..878630 (+) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A514ELX1 |
Locus tag | DSD31_RS04340 | Protein ID | WP_004867358.1 |
Coordinates | 877973..878239 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DSD31_RS04315 | 873108..874541 | - | 1434 | WP_004867372.1 | 6-phospho-beta-glucosidase | - |
DSD31_RS04320 | 874661..875389 | - | 729 | WP_004867368.1 | MurR/RpiR family transcriptional regulator | - |
DSD31_RS04325 | 875439..875750 | + | 312 | WP_004867365.1 | N(4)-acetylcytidine aminohydrolase | - |
DSD31_RS04330 | 875912..876571 | + | 660 | WP_004867362.1 | hemolysin III family protein | - |
DSD31_RS04335 | 876693..877676 | - | 984 | WP_004867359.1 | tRNA-modifying protein YgfZ | - |
DSD31_RS04340 | 877973..878239 | + | 267 | WP_004867358.1 | FAD assembly factor SdhE | Antitoxin |
DSD31_RS04345 | 878220..878630 | + | 411 | WP_004867355.1 | protein YgfX | Toxin |
DSD31_RS04350 | 878638..879159 | - | 522 | WP_004867353.1 | flavodoxin FldB | - |
DSD31_RS04355 | 879337..880233 | + | 897 | WP_015585784.1 | site-specific tyrosine recombinase XerD | - |
DSD31_RS04360 | 880256..880969 | + | 714 | WP_004867349.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
DSD31_RS04365 | 880975..882708 | + | 1734 | WP_015585785.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 16226.16 Da Isoelectric Point: 11.3349
>T108121 WP_004867355.1 NZ_CP030874:878220-878630 [Raoultella sp. X13]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWIAADSMDAKEWRDLRRLVLQKPAQE
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWIAADSMDAKEWRDLRRLVLQKPAQE
Download Length: 411 bp
>T108121 NZ_CP030874:878220-878630 [Raoultella sp. X13]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCCTGGCGCTCACAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTGCTGCTGATGCCCTGGCCGCTGAGCTACACGCCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGTCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGATCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTGTTACAAAAACCGG
CACAGGAGTAA
GTGGTCCTGTGGCAATCTGATTTACGCATCTCCTGGCGCTCACAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTGCTGCTGATGCCCTGGCCGCTGAGCTACACGCCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGTCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGATCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTGTTACAAAAACCGG
CACAGGAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10553.05 Da Isoelectric Point: 4.8432
>AT108121 WP_004867358.1 NZ_CP030874:877973-878239 [Raoultella sp. X13]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI
Download Length: 267 bp
>AT108121 NZ_CP030874:877973-878239 [Raoultella sp. X13]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGATC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCGCAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGATC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCGCAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A808XTM6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A514ELX1 |