Detailed information of TA system TA107256

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 102217..102761
• Replicon: chromosome
• Accession: NZ_CP030164
• Organism: Xanthomonas citri pv. punicae strain LMG7439

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: XapA_RS00465
• Protein ID: WP_005928957.1
• Coordinates: 102462..102761 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A6M2XLH9
• Locus tag: XapA_RS00460
• Protein ID: WP_005928960.1
• Coordinates: 102217..102474 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XapA_RS00445	97333..98814	-	1482	WP_033480176.1	ribonuclease H-like domain-containing protein	-
XapA_RS00450	98811..101309	-	2499	WP_005928965.1	DEAD/DEAH box helicase	-
XapA_RS00455	101487..102149	+	663	WP_005912558.1	hemolysin III family protein	-
XapA_RS00460	102217..102474	+	258	WP_005928960.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XapA_RS00465	102462..102761	+	300	WP_005928957.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XapA_RS00475	102940..103839	-	900	WP_005928955.1	SDR family NAD(P)-dependent oxidoreductase	-
XapA_RS00480	103898..104635	-	738	WP_033480174.1	SDR family oxidoreductase	-
XapA_RS24070	104649..104870	-	222	WP_172637392.1	hypothetical protein	-
XapA_RS00485	104761..105671	+	911	Protein_90	LysR family transcriptional regulator	-
XapA_RS00490	105871..106581	+	711	WP_050550563.1	hypothetical protein	-
XapA_RS00495	106780..107427	-	648	WP_033480173.1	NAD(P)H-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	107490..108452	962

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T107256 WP_005928957.1 NZ_CP030164:102462-102761 [Xanthomonas citri pv. punicae]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHIMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T107256 NZ_CP030164:102462-102761 [Xanthomonas citri pv. punicae]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACATCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9659.15 Da
• Isoelectric Point: 8.6223

>AT107256 WP_005928960.1 NZ_CP030164:102217-102474 [Xanthomonas citri pv. punicae]
MRTELVTTLKRQANELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT107256 NZ_CP030164:102217-102474 [Xanthomonas citri pv. punicae]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGAACGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A6M2XLH9