Detailed information of TA system TA106852

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3252955..3253868
• Replicon: chromosome
• Accession: NZ_CP030007
• Organism: Enterobacter hormaechei subsp. xiangfangensis strain Pb204

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DN066_RS15930
• Protein ID: WP_032647883.1
• Coordinates: 3253395..3253868 (+)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DN066_RS15925
• Protein ID: WP_023296216.1
• Coordinates: 3252955..3253398 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DN066_RS15910	3248883..3250604	+	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
DN066_RS15915	3250650..3251354	+	705	WP_032647884.1	leucyl/phenylalanyl-tRNA--protein transferase	-
DN066_RS15920	3251639..3251857	+	219	WP_002211347.1	translation initiation factor IF-1	-
DN066_RS15925	3252955..3253398	+	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
DN066_RS15930	3253395..3253868	+	474	WP_032647883.1	RES domain-containing protein	Toxin
DN066_RS15935	3253891..3254444	-	554	Protein_3038	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
DN066_RS15940	3254454..3255452	-	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
DN066_RS15945	3255466..3256401	-	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
DN066_RS15950	3256398..3257708	-	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T106852 WP_032647883.1 NZ_CP030007:3253395-3253868 [Enterobacter hormaechei subsp. xiangfangensis]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T106852 NZ_CP030007:3253395-3253868 [Enterobacter hormaechei subsp. xiangfangensis]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT106852 WP_023296216.1 NZ_CP030007:3252955-3253398 [Enterobacter hormaechei subsp. xiangfangensis]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT106852 NZ_CP030007:3252955-3253398 [Enterobacter hormaechei subsp. xiangfangensis]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA